Abstract
We present a case of transient abnormal myelopoiesis (TAM) presenting as non-immune fetal hydrops (NIHF). Hydrops fetalis (HF) is a condition associated with very high perinatal mortality, especially when no treatable cause, such as fetal anaemia, exists. In fetuses prior to 24 weeks with NIHF, a chromosomal anomaly is a common association. TAM is a leukaemic condition, almost entirely limited to children with Down syndrome. The presentation of TAM prenatally is unusual but cases may present ultrasonographically with NIHF and associated fetal hepatosplenomegaly. We report a case presenting in this manner with NIHF detected at 29 weeks' gestation and discuss the subsequent diagnosis and management of in utero TAM. Copyright (C) 2010 S. Karger AG, Basel
Original language | English |
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Pages (from-to) | 171-173 |
Number of pages | 3 |
Journal | Fetal Diagnosis and Therapy |
Volume | 27 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jan 2010 |
Keywords
- Down syndrome
- Myelopoiesis, transient abnormal
- Hydrops fetalis
- Fetal hydrops, non-immune