Tracking the chiral recognition of adsorbed dipeptides at the single-molecule level

Magalí Lingenfelder; Giulia Tomba; Giovanni Costantini; Lucio Colombi Ciacchi; Alessandro De Vita; Klaus Kern

doi:10.1002/anie.200700194

Tracking the chiral recognition of adsorbed dipeptides at the single-molecule level

Magalí Lingenfelder^*
, Giulia Tomba
, Giovanni Costantini
, Lucio Colombi Ciacchi
, Alessandro De Vita
, Klaus Kern

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

141 Citations (Scopus)

Abstract

Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D-Phe-D-Phe, L: L-Phe-L-Phe). With STM movies, the chiral-recognition process of individual adsorbed di-phenylalanine molecules is followed to illustrate the dynamic induced-fit mechanism at the single-molecule level.

Original language	English
Pages (from-to)	4492-4495
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	46
Issue number	24
DOIs	https://doi.org/10.1002/anie.200700194
Publication status	Published - 2007

Keywords

Chirality
Density functional calculations
Molecular recognition
Peptides
Scanning probe microscopy

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200700194

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abstract = "Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D-Phe-D-Phe, L: L-Phe-L-Phe). With STM movies, the chiral-recognition process of individual adsorbed di-phenylalanine molecules is followed to illustrate the dynamic induced-fit mechanism at the single-molecule level.",

keywords = "Chirality, Density functional calculations, Molecular recognition, Peptides, Scanning probe microscopy",

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AU - Lingenfelder, Magalí

AU - Tomba, Giulia

AU - Costantini, Giovanni

AU - Ciacchi, Lucio Colombi

AU - De Vita, Alessandro

AU - Kern, Klaus

PY - 2007

Y1 - 2007

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AB - Lights, camera, action! The general mechanism of biomolecular recognition introduced by Pauling more than 50 years ago has now been brought to the movie screen (see still frame; D: D-Phe-D-Phe, L: L-Phe-L-Phe). With STM movies, the chiral-recognition process of individual adsorbed di-phenylalanine molecules is followed to illustrate the dynamic induced-fit mechanism at the single-molecule level.

KW - Chirality

KW - Density functional calculations

KW - Molecular recognition

KW - Peptides

KW - Scanning probe microscopy

UR - https://www.scopus.com/pages/publications/34250691434

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JF - Angewandte Chemie - International Edition

IS - 24

ER -

Tracking the chiral recognition of adsorbed dipeptides at the single-molecule level

Abstract

Keywords

ASJC Scopus subject areas

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