Therapeutic nanoparticles in clinics and under clinical evaluation

C.A. Schütz, L. Juillerat-Jeanneret, H. Mueller, I. Lynch, M. Riediker

Research output: Contribution to journalArticlepeer-review

160 Citations (Scopus)


This article reviews nanoparticulate-chemotherapeutic systems that have been developed for human therapy, considering the components of the nanoparticles, the therapeutic agents associated with the nanoparticles and the clinical indications these therapeutic nanoparticles have been developed for. In this evaluation we have put into perspective the types of nanomaterials and their therapeutic indications. We have reviewed the nanoparticulate- chemotherapeutic systems that have been published, approved and marketed and that are currently in clinical use. We have also analyzed the nanoparticulate-chemotherapeutic systems that are in clinical trials and under preclinical development.
Original languageEnglish
Pages (from-to)449-467
Number of pages19
Issue number3
Publication statusPublished - 1 Mar 2013

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Copyright 2013 Elsevier B.V., All rights reserved.


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