The Type 1 diabetes 'honeymoon' period is five times longer in men who exercise: a case-control study

M R Chetan, M H Charlton, C Thompson, R P Dias, R C Andrews, P Narendran

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4 Citations (Scopus)
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Abstract

Type 1 diabetes mellitus is an autoimmune disorder characterized by the destruction of insulin-secreting β cells, and subsequent insulin deficiency. Shortly after diagnosis, 60% of adults with Type 1 diabetes experience a period of partial remission, or 'honeymoon' period, characterized by low insulin requirement and good glycaemic control [1]. Historically, the honeymoon period was defined as an insulin requirement of ≤ 0.5 units/kg/day together with HbA1c ≤ 58 mmol/mol (7.5%). Currently, the honeymoon period is defined as insulin dose-adjusted A1c (IDAA1c ) ≤ 9, where IDAA1c = HbA1c (%) + [4× insulin dose (units/kg/day)] [2]. This shows good correlation with stimulated C-peptide, and therefore endogenous insulin secretion [2]. This article is protected by copyright. All rights reserved.

Original languageEnglish
JournalDiabetic Medicine
Early online date17 Aug 2018
DOIs
Publication statusE-pub ahead of print - 17 Aug 2018

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