The transcriptome of enterohaemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

S Dahan; Stuart Knutton; Robert Shaw; VF Crepin; G Dougan; G Frankel

doi:10.1128/IAI.72.9.5452-5459.2004

The transcriptome of enterohaemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

S Dahan, Stuart Knutton, Robert Shaw, VF Crepin, G Dougan, G Frankel

Biosciences

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60 Citations (Scopus)

Abstract

Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

Original language	English
Pages (from-to)	5452-5459
Number of pages	8
Journal	Infection and Immunity
Volume	72
DOIs	https://doi.org/10.1128/IAI.72.9.5452-5459.2004
Publication status	Published - 1 Jan 2004

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10.1128/IAI.72.9.5452-5459.2004

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title = "The transcriptome of enterohaemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes",

abstract = "Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.",

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AU - Dahan, S

AU - Knutton, Stuart

AU - Shaw, Robert

AU - Crepin, VF

AU - Dougan, G

AU - Frankel, G

PY - 2004/1/1

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AB - Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.

UR - https://www.scopus.com/pages/publications/4544220703

U2 - 10.1128/IAI.72.9.5452-5459.2004

DO - 10.1128/IAI.72.9.5452-5459.2004

M3 - Article

C2 - 15322044

VL - 72

SP - 5452

EP - 5459

JO - Infection and Immunity

JF - Infection and Immunity

ER -

The transcriptome of enterohaemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes

Abstract

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