Abstract
As described in an accompanying paper, trinitrophenyl (TNP) modification of pork insulin (PI) at the A1 glycine position allows this molecule to stimulate a proliferative response in H-2b (B10) mice. We now show that this antigen stimulates low IgG responses in the same strain of mice. Our results show that T-cell help and proliferation may therefore be regulated independently.
Original language | English |
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Pages (from-to) | 45-8 |
Number of pages | 4 |
Journal | Immunology |
Volume | 66 |
Issue number | 1 |
Publication status | Published - Jan 1989 |
Keywords
- Adoptive Transfer
- Animals
- Antibodies
- Antibody Formation
- B-Lymphocytes
- Cattle
- Cell Proliferation
- Insulin
- Mice
- Mice, Inbred Strains
- Swine
- T-Lymphocytes