The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Denis Glotz; Jeremy R Chapman; Vikas R Dharnidharka; Douglas W Hanto; Maria C R Castro; Hans H Hirsch; Véronique Leblond; Aneesh K Mehta; Bruno Moulin; Antonio Pagliuca; Julio Pascual; Alan B Rickinson; Francesco P Russo; Ralf U Trappe; Angela C Webster; Andreas O Zuckermann; Thomas G Gross

doi:10.1097/TP.0b013e318269e64f

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Denis Glotz, Jeremy R Chapman, Vikas R Dharnidharka, Douglas W Hanto, Maria C R Castro, Hans H Hirsch, Véronique Leblond, Aneesh K Mehta, Bruno Moulin, Antonio Pagliuca, Julio Pascual, Alan B Rickinson, Francesco P Russo, Ralf U Trappe, Angela C Webster, Andreas O Zuckermann, Thomas G Gross

Cancer and Genomic Sciences

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

: Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.

Original language	English
Pages (from-to)	784-793
Number of pages	10
Journal	Transplantation
Volume	94
Issue number	8
DOIs	https://doi.org/10.1097/TP.0b013e318269e64f
Publication status	Published - 2012

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Glotz, D., Chapman, J. R., Dharnidharka, V. R., Hanto, D. W., Castro, M. C. R., Hirsch, H. H., Leblond, V., Mehta, A. K., Moulin, B., Pagliuca, A., Pascual, J., Rickinson, A. B., Russo, F. P., Trappe, R. U., Webster, A. C., Zuckermann, A. O., & Gross, T. G. (2012). The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders. Transplantation, 94(8), 784-793. https://doi.org/10.1097/TP.0b013e318269e64f

@article{31be4a2a06ac48019b94770d4583dde1,

title = "The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders",

abstract = ": Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.",

author = "Denis Glotz and Chapman, {Jeremy R} and Dharnidharka, {Vikas R} and Hanto, {Douglas W} and Castro, {Maria C R} and Hirsch, {Hans H} and V{\'e}ronique Leblond and Mehta, {Aneesh K} and Bruno Moulin and Antonio Pagliuca and Julio Pascual and Rickinson, {Alan B} and Russo, {Francesco P} and Trappe, {Ralf U} and Webster, {Angela C} and Zuckermann, {Andreas O} and Gross, {Thomas G}",

year = "2012",

doi = "10.1097/TP.0b013e318269e64f",

language = "English",

volume = "94",

pages = "784--793",

journal = "Transplantation",

publisher = "Lippincott Williams and Wilkins",

number = "8",

}

Glotz, D, Chapman, JR, Dharnidharka, VR, Hanto, DW, Castro, MCR, Hirsch, HH, Leblond, V, Mehta, AK, Moulin, B, Pagliuca, A, Pascual, J, Rickinson, AB, Russo, FP, Trappe, RU, Webster, AC, Zuckermann, AO & Gross, TG 2012, 'The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders', Transplantation, vol. 94, no. 8, pp. 784-793. https://doi.org/10.1097/TP.0b013e318269e64f

TY - JOUR

T1 - The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

AU - Glotz, Denis

AU - Chapman, Jeremy R

AU - Dharnidharka, Vikas R

AU - Hanto, Douglas W

AU - Castro, Maria C R

AU - Hirsch, Hans H

AU - Leblond, Véronique

AU - Mehta, Aneesh K

AU - Moulin, Bruno

AU - Pagliuca, Antonio

AU - Pascual, Julio

AU - Rickinson, Alan B

AU - Russo, Francesco P

AU - Trappe, Ralf U

AU - Webster, Angela C

AU - Zuckermann, Andreas O

AU - Gross, Thomas G

PY - 2012

Y1 - 2012

N2 - : Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.

AB - : Posttransplant lymphoproliferative disorders (PTLDs) are associated with significant morbidity and mortality among solid-organ transplant patients, but approaches to diagnosis and management vary considerably. An international multidisciplinary panel evaluated current understanding of risk factors and classification systems and developed recommendations to aid in PTLD prevention. We considered evidence on PTLD risk factors including Epstein-Barr virus serostatus and immunosuppression and identified knowledge gaps for future research. Recommendations address prophylactic and preemptive strategies to minimize PTLD development, including modulation of immunosuppression and antiviral drug regimens. Finally, new classification criteria were outlined that may help facilitate standardized reporting and improve our understanding of PTLD.

U2 - 10.1097/TP.0b013e318269e64f

DO - 10.1097/TP.0b013e318269e64f

M3 - Article

C2 - 22992767

VL - 94

SP - 784

EP - 793

JO - Transplantation

JF - Transplantation

IS - 8

ER -

The Seville Expert Workshop for Progress in Posttransplant Lymphoproliferative Disorders

Abstract

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