The role of strut chordae in mitral valve competence during annular dilation

Samuel Taylor, Keith G. Buchan, Daniel M. Espino*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
138 Downloads (Pure)

Abstract

Strut chordae, on their own, are not typically thought to aid mitral valve competence. The aim of this study is to assess whether strut chordae aid mitral valve competence during acute annular dilation. Twelve porcine hearts were dissected and tested using an in vitro simulator, with the mitral annulus tested in either a ‘normal’ or a dilated configuration. The normal configuration included a diameter of 30 mm, a posterior leaflet ‘radius’ of 15 mm and a commissural corner ‘radius’ of 7.5 mm; the dilated annular template instead used dimensions of 50 mm, 25 mm and 12.5 mm, respectively. Each mitral valve underwent ten repeat tests with a target systolic pressure of 100 mmHg. No significant difference in the pressure was detected between the dilated and regular annuli for the mitral valves tested (95 ± 3 mmHg cf. 95 ± 2 mmHg). However, the volume of regurgitation for a dilated annulus was 28 ml greater than for a valve with a normal annulus. Following severing of strut chordae, there was a significant reduction in the systolic pressure withstood before regurgitation by mitral valves with dilated annuli (60 ± 29 mmHg cf. 95 ± 2 mmHg for normal annular dimensions; p < 0.05). In conclusion, strut chordae tendineae may play a role in aiding mitral valve competence during pathophysiology.

Original languageEnglish
JournalPerfusion (United Kingdom)
Early online date22 Jul 2020
DOIs
Publication statusE-pub ahead of print - 22 Jul 2020

Keywords

  • annular dilation
  • chordae tendineae
  • mitral valve
  • regurgitation
  • strut chordae

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

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