The role of acetic acid in orthopaedic surgery

Yousuf Hashmi*, Andrew Kailin Zhou, Anam Jawaid, Anli Yue Zhou, Vianca Shah, Azeem Thahir, Matija Krkovic

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Downloads (Pure)


Acetic acid has become more commonly used in orthopaedic surgery. The purposed roles include biofilm eradication and surgical debridement, postoperative scar reduction and managing soft tissue injuries. Current research is scarce and does not provide conclusive evidence behind acetic acid's efficacy in orthopaedic procedures such as biofilm eradication or acetic acid iontophoresis in soft tissue injuries. Current literature on acetic acid's effects on biofilm eradication is composed of in-vitro studies, which do not demonstrate the potential clinical efficacy of acetic acid. Acetic acid iontophoresis is a novel technique which is now more commonly accepted for soft tissues injuries. Our literature search identified calcifying tendonitis of the shoulder, rotator cuff tendinopathy, heel pain syndrome, plantar fasciitis, achilles tendonitis, calcifying tendonitis of the ankle, myositis ossificans and cervical spondylosis as documented clinical uses. In this narrative review, we present the current uses of acetic acid and acetic acid iontophoresis, while evaluating the evidence revolving around its efficacy, benefits and risks.

Original languageEnglish
Number of pages5
JournalJournal of perioperative practice
Early online date26 Jul 2021
Publication statusE-pub ahead of print - 26 Jul 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s) 2021.


  • Debridement
  • Iontophoresis
  • Soft tissue injuries

ASJC Scopus subject areas

  • Surgery
  • Medical–Surgical
  • Anesthesiology and Pain Medicine


Dive into the research topics of 'The role of acetic acid in orthopaedic surgery'. Together they form a unique fingerprint.

Cite this