The psychopathological spectrum of Gilles de la Tourette syndrome

Andrea E Cavanna, Hugh Rickards

Research output: Contribution to journalReview articlepeer-review

74 Citations (Scopus)

Abstract

Gilles de la Tourette syndrome (GTS) holds a unique status as quintessentially neuropsychiatric condition at the interface between neurology (movement disorder) and psychiatry (behavioural condition). This is a reflection of the common observation that the vast majority of patients present with behavioural problems in association with the motor and vocal tics which define GTS. The present article focuses on the relationship between GTS and obsessive-compulsive disorder (OCD), attention-deficit and hyperactivity disorder (ADHD), affective disorders (both major depression and bipolar affective disorder), and personality disorders. Over the last decade, converging lines of research have pointed towards the concept of a 'GTS spectrum', encompassing motor phenomena and behavioural symptoms, with important implications for the clinical management of patients.

Original languageEnglish
Pages (from-to)1008-15
Number of pages8
JournalNeuroscience and biobehavioral reviews
Volume37
Issue number6
DOIs
Publication statusPublished - Jul 2013

Keywords

  • Attention Deficit Disorder with Hyperactivity/complications
  • Humans
  • Mood Disorders/complications
  • Obsessive-Compulsive Disorder/complications
  • Psychopathology
  • Tourette Syndrome/complications

Fingerprint

Dive into the research topics of 'The psychopathological spectrum of Gilles de la Tourette syndrome'. Together they form a unique fingerprint.

Cite this