The Potential Impact of Essential Nutrients Vitamins C and D upon Periodontal Disease Pathogenesis and Therapeutic Outcomes

Gareth Brock, Iain Chapple

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)
541 Downloads (Pure)

Abstract

Diet has powerful effects upon inflammatory status, arguably as strong or stronger than microbial plaque. Despite a relationship between diet and periodontal inflammatory markers being established over 30 years ago, it is only recently that the mechanisms underpinning these effects have begun to be examined in detail. Following an analysis of the evidence base in 2011, this review focuses upon the most contemporaneous evidence relating specifically to the micronutrient vitamins C and D and their potential impact upon periodontal disease pathogenesis and/or therapeutic outcomes. The authors bring together both epidemiological and laboratory data and aim to outline avenues for potential studies given the limited number of larger well-conducted clinical interventional trials completed to date.
Original languageEnglish
Pages (from-to)337-346
Number of pages10
JournalCurrent Oral Health Reports
Volume3
Issue number4
Early online date7 Oct 2016
DOIs
Publication statusPublished - Dec 2016

Keywords

  • Periodontitis
  • Micronutrients
  • Dietary supplements
  • Vitamin C
  • Ascorbic acid
  • Vitamin D

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