The phototherapy toward corneal neovascularization elimination: An efficient, selective and safe strategy

Jingwen Yu; Chengchao Chu; Yiming Wu; Gang Liu; Wei Li

doi:10.1016/j.cclet.2020.11.025

The phototherapy toward corneal neovascularization elimination: An efficient, selective and safe strategy

Jingwen Yu, Chengchao Chu, Yiming Wu, Gang Liu^*, Wei Li^*

^*Corresponding author for this work

Biomedical Sciences

Research output: Contribution to journal › Letter › peer-review

Abstract

Corneal neovascularization (CNV) can induce severe visual impairment and even blindness. Current treatments have limited efficacy and some undesirable side effects. Phototherapy (PT) is a modern medical technique in CNV treatment and worth further improvement. Nanotechnology has various advantages and nanoparticle-mediated drug delivery also contributes to CNV elimination. Phototherapy combined with functional nanoparticles featuring photoacoustic imaging contrast properties can accomplish accurate and safe inhibition of CNV, thus is promising in clinical application.

Original language	English
Pages (from-to)	99-101
Number of pages	3
Journal	Chinese Chemical Letters
Volume	32
Issue number	1
Early online date	20 Nov 2020
DOIs	https://doi.org/10.1016/j.cclet.2020.11.025
Publication status	Published - Jan 2021

Bibliographical note

Acknowledgments:
This study was supported in part by the National Key R&D Program of China (Nos. 2018YFA0107301 and 2018YFA0107304), the National Natural Science Foundation of China (NSFC, Nos. 81770894, 81901876, 81470602 and 81330022) and the Fundamental Research Funds for the Central Universities (Nos. 20720190088 and 20720200019), the Medical and Health Key Project of Xiamen (No. 3502Z20191106), and the Program for New Century Excellent Talents in University, China (No. NCET-13-0502).

Keywords

Corneal neovascularization
Phototherapy
Nanotechnology
R-nanoICG
Photoacoustic imaging

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10.1016/j.cclet.2020.11.025Licence: None: All rights reserved

Cite this

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title = "The phototherapy toward corneal neovascularization elimination: An efficient, selective and safe strategy",

abstract = "Corneal neovascularization (CNV) can induce severe visual impairment and even blindness. Current treatments have limited efficacy and some undesirable side effects. Phototherapy (PT) is a modern medical technique in CNV treatment and worth further improvement. Nanotechnology has various advantages and nanoparticle-mediated drug delivery also contributes to CNV elimination. Phototherapy combined with functional nanoparticles featuring photoacoustic imaging contrast properties can accomplish accurate and safe inhibition of CNV, thus is promising in clinical application.",

keywords = "Corneal neovascularization, Phototherapy, Nanotechnology, R-nanoICG, Photoacoustic imaging",

author = "Jingwen Yu and Chengchao Chu and Yiming Wu and Gang Liu and Wei Li",

note = "Acknowledgments: This study was supported in part by the National Key R&D Program of China (Nos. 2018YFA0107301 and 2018YFA0107304), the National Natural Science Foundation of China (NSFC, Nos. 81770894, 81901876, 81470602 and 81330022) and the Fundamental Research Funds for the Central Universities (Nos. 20720190088 and 20720200019), the Medical and Health Key Project of Xiamen (No. 3502Z20191106), and the Program for New Century Excellent Talents in University, China (No. NCET-13-0502).",

year = "2021",

month = jan,

doi = "10.1016/j.cclet.2020.11.025",

language = "English",

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T2 - An efficient, selective and safe strategy

AU - Yu, Jingwen

AU - Chu, Chengchao

AU - Wu, Yiming

AU - Liu, Gang

AU - Li, Wei

N1 - Acknowledgments: This study was supported in part by the National Key R&D Program of China (Nos. 2018YFA0107301 and 2018YFA0107304), the National Natural Science Foundation of China (NSFC, Nos. 81770894, 81901876, 81470602 and 81330022) and the Fundamental Research Funds for the Central Universities (Nos. 20720190088 and 20720200019), the Medical and Health Key Project of Xiamen (No. 3502Z20191106), and the Program for New Century Excellent Talents in University, China (No. NCET-13-0502).

PY - 2021/1

Y1 - 2021/1

N2 - Corneal neovascularization (CNV) can induce severe visual impairment and even blindness. Current treatments have limited efficacy and some undesirable side effects. Phototherapy (PT) is a modern medical technique in CNV treatment and worth further improvement. Nanotechnology has various advantages and nanoparticle-mediated drug delivery also contributes to CNV elimination. Phototherapy combined with functional nanoparticles featuring photoacoustic imaging contrast properties can accomplish accurate and safe inhibition of CNV, thus is promising in clinical application.

AB - Corneal neovascularization (CNV) can induce severe visual impairment and even blindness. Current treatments have limited efficacy and some undesirable side effects. Phototherapy (PT) is a modern medical technique in CNV treatment and worth further improvement. Nanotechnology has various advantages and nanoparticle-mediated drug delivery also contributes to CNV elimination. Phototherapy combined with functional nanoparticles featuring photoacoustic imaging contrast properties can accomplish accurate and safe inhibition of CNV, thus is promising in clinical application.

KW - Corneal neovascularization

KW - Phototherapy

KW - Nanotechnology

KW - R-nanoICG

KW - Photoacoustic imaging

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DO - 10.1016/j.cclet.2020.11.025

M3 - Letter

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EP - 101

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 1

ER -

The phototherapy toward corneal neovascularization elimination: An efficient, selective and safe strategy

Abstract

Bibliographical note

Keywords

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