The natural history of cervical HPV infection: unresolved issues

Ciaran Woodman, Stuart Collins, Lawrence Young

Research output: Contribution to journalArticle

660 Citations (Scopus)


The identification of high-risk human papillomavirus (HPV) types as a necessary cause of cervical cancer offers the prospect of effective primary prevention and the possibility of improving the efficiency of cervical screening programmes. However, for these opportunities to be realized, a more complete understanding of the natural history of HPV infection, and its relationship to the development of epithelial abnormalities of the cervix, is required. We discuss areas of uncertainty, and their possible effect on disease prevention strategies.
Original languageEnglish
Pages (from-to)11-22
Number of pages12
JournalNature Reviews Cancer
Issue number1
Publication statusPublished - 1 Jan 2007


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