The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study

Ankie Lebon; Nelianne J Verkaik; Corné P de Vogel; Herbert Hooijkaas; Henri A Verbrugh; Willem J B van Wamel; Vincent W V Jaddoe; Albert Hofman; Peter W M Hermans; Tim J Mitchell; Henriette A Moll; Alex van Belkum

doi:10.1128/CVI.00357-10

The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study

Ankie Lebon, Nelianne J Verkaik, Corné P de Vogel, Herbert Hooijkaas, Henri A Verbrugh, Willem J B van Wamel, Vincent W V Jaddoe, Albert Hofman, Peter W M Hermans, Tim J Mitchell, Henriette A Moll, Alex van Belkum

Immunology and Immunotherapy

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.

Original language	English
Pages (from-to)	180-3
Number of pages	4
Journal	Clinical and Vaccine Immunology
Volume	18
Issue number	1
DOIs	https://doi.org/10.1128/CVI.00357-10
Publication status	Published - Jan 2011

Keywords

Antibodies, Bacterial
Carrier State
Cohort Studies
Humans
Infant
Longitudinal Studies
Nasopharynx
Netherlands
Pneumococcal Infections
Prevalence
Staphylococcal Infections
Staphylococcus aureus
Streptococcus pneumoniae

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1128/CVI.00357-10

Cite this

Lebon, A., Verkaik, N. J., de Vogel, C. P., Hooijkaas, H., Verbrugh, H. A., van Wamel, W. J. B., Jaddoe, V. W. V., Hofman, A., Hermans, P. W. M., Mitchell, T. J., Moll, H. A., & van Belkum, A. (2011). The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study. Clinical and Vaccine Immunology, 18(1), 180-3. https://doi.org/10.1128/CVI.00357-10

@article{8c1a735b9a82460e906d598d4bd76e01,

title = "The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study",

abstract = "Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.",

keywords = "Antibodies, Bacterial, Carrier State, Cohort Studies, Humans, Infant, Longitudinal Studies, Nasopharynx, Netherlands, Pneumococcal Infections, Prevalence, Staphylococcal Infections, Staphylococcus aureus, Streptococcus pneumoniae",

author = "Ankie Lebon and Verkaik, {Nelianne J} and {de Vogel}, {Corn{\'e} P} and Herbert Hooijkaas and Verbrugh, {Henri A} and {van Wamel}, {Willem J B} and Jaddoe, {Vincent W V} and Albert Hofman and Hermans, {Peter W M} and Mitchell, {Tim J} and Moll, {Henriette A} and {van Belkum}, Alex",

year = "2011",

month = jan,

doi = "10.1128/CVI.00357-10",

language = "English",

volume = "18",

pages = "180--3",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "1",

}

Lebon, A, Verkaik, NJ, de Vogel, CP, Hooijkaas, H, Verbrugh, HA, van Wamel, WJB, Jaddoe, VWV, Hofman, A, Hermans, PWM, Mitchell, TJ, Moll, HA & van Belkum, A 2011, 'The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study', Clinical and Vaccine Immunology, vol. 18, no. 1, pp. 180-3. https://doi.org/10.1128/CVI.00357-10

The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study. / Lebon, Ankie; Verkaik, Nelianne J; de Vogel, Corné P et al.
In: Clinical and Vaccine Immunology, Vol. 18, No. 1, 01.2011, p. 180-3.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study

AU - Lebon, Ankie

AU - Verkaik, Nelianne J

AU - de Vogel, Corné P

AU - Hooijkaas, Herbert

AU - Verbrugh, Henri A

AU - van Wamel, Willem J B

AU - Jaddoe, Vincent W V

AU - Hofman, Albert

AU - Hermans, Peter W M

AU - Mitchell, Tim J

AU - Moll, Henriette A

AU - van Belkum, Alex

PY - 2011/1

Y1 - 2011/1

N2 - Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.

AB - Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.

KW - Antibodies, Bacterial

KW - Carrier State

KW - Cohort Studies

KW - Humans

KW - Infant

KW - Longitudinal Studies

KW - Nasopharynx

KW - Netherlands

KW - Pneumococcal Infections

KW - Prevalence

KW - Staphylococcal Infections

KW - Staphylococcus aureus

KW - Streptococcus pneumoniae

U2 - 10.1128/CVI.00357-10

DO - 10.1128/CVI.00357-10

M3 - Article

C2 - 21084460

SN - 1556-6811

VL - 18

SP - 180

EP - 183

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 1

ER -

The inverse correlation between Staphylococcus aureus and Streptococcus pneumoniae colonization in infants is not explained by differences in serum antibody levels in the Generation R Study

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this