The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials

E Palcevskis; A Dindune; Y Dekhtyar; N Polyaka; D Veljović; Rachel Sammons

doi:10.1088/1757-899X/23/1/012032

The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials

E Palcevskis, A Dindune, Y Dekhtyar, N Polyaka, D Veljović, Rachel Sammons

Dentistry

Research output: Contribution to journal › Conference article

6 Citations (Scopus)

Abstract

The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn⁺²) and with magnesium (Mg⁺²) - all axially pressed and conventionally sintered for 2 h at 1200 deg. C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 deg. C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge

Original language	English
Article number	012032
Number of pages	6
Journal	IOP Conference Series: Materials Science and Engineering
Volume	23
Issue number	1
DOIs	https://doi.org/10.1088/1757-899X/23/1/012032
Publication status	Published - 23 Jun 2011
Event	Annual Conference on Functional Materials and Nanotechnologies - Riga, Latvia Duration: 5 Apr 2011 → 8 Apr 2011

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title = "The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials",

abstract = "The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 deg. C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 deg. C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge",

author = "E Palcevskis and A Dindune and Y Dekhtyar and N Polyaka and D Veljovi{\'c} and Rachel Sammons",

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TY - JOUR

T1 - The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials

AU - Palcevskis, E

AU - Dindune, A

AU - Dekhtyar, Y

AU - Polyaka, N

AU - Veljović, D

AU - Sammons, Rachel

PY - 2011/6/23

Y1 - 2011/6/23

N2 - The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 deg. C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 deg. C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge

AB - The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 deg. C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 deg. C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge

U2 - 10.1088/1757-899X/23/1/012032

DO - 10.1088/1757-899X/23/1/012032

M3 - Conference article

SN - 1757-899X

VL - 23

JO - IOP Conference Series: Materials Science and Engineering

JF - IOP Conference Series: Materials Science and Engineering

IS - 1

M1 - 012032

T2 - Annual Conference on Functional Materials and Nanotechnologies

Y2 - 5 April 2011 through 8 April 2011

ER -

The influence of surface treatment by hydrogenation on the biocompatibility of different hydroxyapatite materials

Abstract

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