The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat

David Hauton; Andrew Holmes; Oliver Ziff; Prem Kumar

doi:10.1007/s00424-012-1210-z

The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat

David Hauton
, Andrew Holmes
, Oliver Ziff
, Prem Kumar

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Chronic catecholamine production is associated with desensitisation and down-regulation of adrenergic receptors and occurs in conditions, such as heart failure and myocardial infarction. The effects of further acute adrenergic stimulation, which may occur during exercise, and their subsequent effects on chemosensitivity and ventilation are unclear. Chronic isoprenaline (ISO) increased ventilation by 50 % (P

Original language	English
Pages (from-to)	209-219
Number of pages	11
Journal	Pfluegers Archiv: European journal of physiology
Volume	465
Issue number	2
DOIs	https://doi.org/10.1007/s00424-012-1210-z
Publication status	Published - 2013

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abstract = "Chronic catecholamine production is associated with desensitisation and down-regulation of adrenergic receptors and occurs in conditions, such as heart failure and myocardial infarction. The effects of further acute adrenergic stimulation, which may occur during exercise, and their subsequent effects on chemosensitivity and ventilation are unclear. Chronic isoprenaline (ISO) increased ventilation by 50 \% (P ",

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AB - Chronic catecholamine production is associated with desensitisation and down-regulation of adrenergic receptors and occurs in conditions, such as heart failure and myocardial infarction. The effects of further acute adrenergic stimulation, which may occur during exercise, and their subsequent effects on chemosensitivity and ventilation are unclear. Chronic isoprenaline (ISO) increased ventilation by 50 % (P

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The impact of acute and chronic catecholamines on respiratory responses to hypoxic stress in the rat

Abstract

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