Abstract
BACKGROUND: Most patients with heart failure due to left ventricular systolic dysfunction (LVSD) secondary to coronary artery disease (CAD) have evidence of myocardium in jeopardy (reversible ischaemia and/or stunning hibernation). It is not known whether revascularisation in such cases is safe or beneficial. AIMS: To determine whether revascularisation will improve the survival of patients with LVSD and heart failure secondary to CAD and myocardium in jeopardy. METHODS: This is a randomised controlled trial comparing revascularisation or not, in addition to optimal medical therapy with ACE inhibitors, beta-blockers, aldosterone antagonists and an anti-thrombotic agent. Patients must have heart failure requiring treatment with diuretics, a left ventricular ejection fraction
Original language | English |
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Pages (from-to) | 295-303 |
Number of pages | 9 |
Journal | European Journal of Heart Failure |
Volume | 5 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jun 2003 |
Keywords
- revascularisation
- HEART study
- left ventricular systolic dysfunction
- heart failure