The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version

Andrea E Cavanna; Chiara Luoni; Claudia Selvini; Rosanna Blangiardo; Clare M Eddy; Paola R Silvestri; Paola V Calì; Stefano Seri; Umberto Balottin; Francesco Cardona; Renata Rizzo; Cristiano Termine

doi:10.3233/BEN-120274

The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version

Andrea E Cavanna, Chiara Luoni, Claudia Selvini, Rosanna Blangiardo, Clare M Eddy, Paola R Silvestri, Paola V Calì, Stefano Seri, Umberto Balottin, Francesco Cardona, Renata Rizzo, Cristiano Termine

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

BACKGROUND: Gilles de la Tourette syndrome (GTS) is a chronic childhood-onset neuropsychiatric disorder with a significant impact on patients' health-related quality of life (HR-QOL). Cavanna et al. (Neurology 2008; 71: 1410-1416) developed and validated the first disease-specific HR-QOL assessment tool for adults with GTS (Gilles de la Tourette Syndrome-Quality of Life Scale, GTS-QOL). This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS.

METHODS: A three-stage process involving 75 patients with GTS recruited through three Departments of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds.

RESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability. Internal consistency reliability was high (Cronbach's alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables.

CONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and validity.

Original language	English
Pages (from-to)	95-103
Number of pages	9
Journal	Behavioural neurology
Volume	27
Issue number	1
DOIs	https://doi.org/10.3233/BEN-120274
Publication status	Published - 2013

Keywords

Adolescent
Child
Female
Humans
Interview, Psychological
Italy
Male
Psychometrics/instrumentation
Quality of Life/psychology
Surveys and Questionnaires/standards
Tourette Syndrome/diagnosis

Access to Document

10.3233/BEN-120274

Cite this

Cavanna, A. E., Luoni, C., Selvini, C., Blangiardo, R., Eddy, C. M., Silvestri, P. R., Calì, P. V., Seri, S., Balottin, U., Cardona, F., Rizzo, R., & Termine, C. (2013). The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version. Behavioural neurology, 27(1), 95-103. https://doi.org/10.3233/BEN-120274

@article{f7937a4075e74b29886d97fa9fe926f8,

title = "The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version",

abstract = "BACKGROUND: Gilles de la Tourette syndrome (GTS) is a chronic childhood-onset neuropsychiatric disorder with a significant impact on patients' health-related quality of life (HR-QOL). Cavanna et al. (Neurology 2008; 71: 1410-1416) developed and validated the first disease-specific HR-QOL assessment tool for adults with GTS (Gilles de la Tourette Syndrome-Quality of Life Scale, GTS-QOL). This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS.METHODS: A three-stage process involving 75 patients with GTS recruited through three Departments of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds.RESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability. Internal consistency reliability was high (Cronbach's alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables.CONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and validity.",

keywords = "Adolescent, Child, Female, Humans, Interview, Psychological, Italy, Male, Psychometrics/instrumentation, Quality of Life/psychology, Surveys and Questionnaires/standards, Tourette Syndrome/diagnosis",

author = "Cavanna, {Andrea E} and Chiara Luoni and Claudia Selvini and Rosanna Blangiardo and Eddy, {Clare M} and Silvestri, {Paola R} and Cal{\`i}, {Paola V} and Stefano Seri and Umberto Balottin and Francesco Cardona and Renata Rizzo and Cristiano Termine",

year = "2013",

doi = "10.3233/BEN-120274",

language = "English",

volume = "27",

pages = "95--103",

journal = "Behavioural neurology",

issn = "0953-4180",

publisher = "IOS Press",

number = "1",

}

Cavanna, AE, Luoni, C, Selvini, C, Blangiardo, R, Eddy, CM, Silvestri, PR, Calì, PV, Seri, S, Balottin, U, Cardona, F, Rizzo, R & Termine, C 2013, 'The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version', Behavioural neurology, vol. 27, no. 1, pp. 95-103. https://doi.org/10.3233/BEN-120274

TY - JOUR

T1 - The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL)

T2 - development and validation of the Italian version

AU - Cavanna, Andrea E

AU - Luoni, Chiara

AU - Selvini, Claudia

AU - Blangiardo, Rosanna

AU - Eddy, Clare M

AU - Silvestri, Paola R

AU - Calì, Paola V

AU - Seri, Stefano

AU - Balottin, Umberto

AU - Cardona, Francesco

AU - Rizzo, Renata

AU - Termine, Cristiano

PY - 2013

Y1 - 2013

N2 - BACKGROUND: Gilles de la Tourette syndrome (GTS) is a chronic childhood-onset neuropsychiatric disorder with a significant impact on patients' health-related quality of life (HR-QOL). Cavanna et al. (Neurology 2008; 71: 1410-1416) developed and validated the first disease-specific HR-QOL assessment tool for adults with GTS (Gilles de la Tourette Syndrome-Quality of Life Scale, GTS-QOL). This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS.METHODS: A three-stage process involving 75 patients with GTS recruited through three Departments of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds.RESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability. Internal consistency reliability was high (Cronbach's alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables.CONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and validity.

AB - BACKGROUND: Gilles de la Tourette syndrome (GTS) is a chronic childhood-onset neuropsychiatric disorder with a significant impact on patients' health-related quality of life (HR-QOL). Cavanna et al. (Neurology 2008; 71: 1410-1416) developed and validated the first disease-specific HR-QOL assessment tool for adults with GTS (Gilles de la Tourette Syndrome-Quality of Life Scale, GTS-QOL). This paper presents the translation, adaptation and validation of the GTS-QOL for young Italian patients with GTS.METHODS: A three-stage process involving 75 patients with GTS recruited through three Departments of Child and Adolescent Neuropsychiatry in Italy led to the development of a 27-item instrument (Gilles de la Tourette Syndrome-Quality of Life Scale in children and adolescents, C&A-GTS-QOL) for the assessment of HR-QOL through a clinician-rated interview for 6-12 year-olds and a self-report questionnaire for 13-18 year-olds.RESULTS: The C&A-GTS-QOL demonstrated satisfactory scaling assumptions and acceptability. Internal consistency reliability was high (Cronbach's alpha > 0.7) and validity was supported by interscale correlations (range 0.4-0.7), principal-component factor analysis and correlations with other rating scales and clinical variables.CONCLUSIONS: The present version of the C&A-GTS-QOL is the first disease-specific HR-QOL tool for Italian young patients with GTS, satisfying criteria for acceptability, reliability and validity.

KW - Adolescent

KW - Child

KW - Female

KW - Humans

KW - Interview, Psychological

KW - Italy

KW - Male

KW - Psychometrics/instrumentation

KW - Quality of Life/psychology

KW - Surveys and Questionnaires/standards

KW - Tourette Syndrome/diagnosis

U2 - 10.3233/BEN-120274

DO - 10.3233/BEN-120274

M3 - Article

C2 - 23598902

SN - 0953-4180

VL - 27

SP - 95

EP - 103

JO - Behavioural neurology

JF - Behavioural neurology

IS - 1

ER -

The Gilles de la Tourette Syndrome-Quality of Life Scale for children and adolescents (C&A-GTS-QOL): development and validation of the Italian version

Abstract

Keywords

Access to Document

Fingerprint

Cite this