TY - JOUR
T1 - The effects of exercise and diurnal variation on monocyte subsets and monocyte-platelet aggregates.
AU - Shantsila, Eduard
AU - Tapp, Luke
AU - Wrigley, BJ
AU - Montoro-Garcia, S
AU - Ghattas, Angie
AU - Jaipersad, Anthony
AU - Lip, Gregory
PY - 2012/2/7
Y1 - 2012/2/7
N2 - Eur J Clin Invest 2012 ABSTRACT: Background Monocytes are important mediators in the pathophysiology of cardiovascular disease, but only scarce data are available on biological and methodological factors affecting their levels. Design Three monocyte subsets, CD14(++) CD16(-) CCR2+ (Mon1), CD14(++) CD16(+) CCR2(+) (Mon2), CD14(+) CD16(+) CCR2(-) (Mon3), and monocyte-platelet aggregates (MPAs) were analysed by flow cytometry. The effects of treadmill exercise were assessed on 12 healthy volunteers. Diurnal variation was evaluated in 16 healthy volunteers, and the effects of delayed blood processing were measured in 12 samples. Results Mon1 were increased when measured 15 min after exercise followed by a reduction at 1 h (P
AB - Eur J Clin Invest 2012 ABSTRACT: Background Monocytes are important mediators in the pathophysiology of cardiovascular disease, but only scarce data are available on biological and methodological factors affecting their levels. Design Three monocyte subsets, CD14(++) CD16(-) CCR2+ (Mon1), CD14(++) CD16(+) CCR2(+) (Mon2), CD14(+) CD16(+) CCR2(-) (Mon3), and monocyte-platelet aggregates (MPAs) were analysed by flow cytometry. The effects of treadmill exercise were assessed on 12 healthy volunteers. Diurnal variation was evaluated in 16 healthy volunteers, and the effects of delayed blood processing were measured in 12 samples. Results Mon1 were increased when measured 15 min after exercise followed by a reduction at 1 h (P
U2 - 10.1111/j.1365-2362.2012.02656.x
DO - 10.1111/j.1365-2362.2012.02656.x
M3 - Article
C2 - 22356533
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
SN - 1365-2362
JO - European journal of clinical investigation
JF - European journal of clinical investigation
ER -
