The development of boronic acids as sensors and separation tools

John S Fossey, Francois D'Hooge, Jean M H van den Elsen, Marta P Pereira Morais, Sofia I Pascu, Steven D Bull, Frank Marken, A Toby A Jenkins, Yun-Bao Jiang, Tony D James

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)


Synthetic receptors for diols that incorporate boronic acid motifs have been developed as new sensors and separation tools. Utilizing the reversible interactions of diols with boronic acids to form boronic esters under new binding regimes has provided new hydrogel constructs that have found use as dye-displacement sensors and electrophoretic separation tools; similarly, molecular boronic-acid-containing chemosensors were constructed that offer applications in the sensing of diols. This review provides a somewhat-personal perspective of developments in boronic-acid-mediated sensing and separation, placed in the context of the seminal works of others in the area, as well as offering a concise summary of the contributions of the co-authors in the area. DOI 10.1002/tcr.201200006.
Original languageEnglish
Pages (from-to)464-78
Number of pages15
JournalThe Chemical Record
Issue number5
Publication statusPublished - 2012


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