The development of anti-cytokine agents for rheumatoid arthritis

Karim Raza, Jonathan Sherlock, Christopher Buckley

Research output: Chapter in Book/Report/Conference proceedingChapter


In this chapter, we will focus on cytokine-based therapeutics. Not only are developments in the identification and targeting of cytokines vital, but the detailed pharmacology of the therapeutics themselves is of critical importance. The proof of concept demonstrated by the success of anti- tumor necrosis factor (TNF) agents, combined with the experimental ease with which cytokines can be investigated and manipulated, has opened the future of rheumatology to exciting new conceptual and therapeutic prospects.
Original languageEnglish
Title of host publicationDevelopment of Therapeutic Agents Handbook
Publication statusPublished - 2012


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