The changing characteristics of COVID-19 presentations: a regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave

Catherine Atkin; Vicky Kamwa; V Reddy-Kolanu; D Parekh; Felicity Evison; Peter Nightingale; Suzy Gallier; Simon Ball; Elizabeth Sapey

doi:10.52964/amja.0848

The changing characteristics of COVID-19 presentations: a regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave

Catherine Atkin, Vicky Kamwa, V Reddy-Kolanu, D Parekh, Felicity Evison, Peter Nightingale, Suzy Gallier, Simon Ball, Elizabeth Sapey

Research output: Contribution to journal › Article › peer-review

Abstract

Background: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus.

Methods: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days.

Results: Wave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions.

Conclusion: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.

Original language	English
Pages (from-to)	92-100
Number of pages	9
Journal	Acute Medicine
Volume	20
Issue number	2
DOIs	https://doi.org/10.52964/amja.0848
Publication status	Published - 6 Jul 2021

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title = "The changing characteristics of COVID-19 presentations: a regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave",

abstract = "Background: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus.Methods: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days.Results: Wave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions.Conclusion: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.",

author = "Catherine Atkin and Vicky Kamwa and V Reddy-Kolanu and D Parekh and Felicity Evison and Peter Nightingale and Suzy Gallier and Simon Ball and Elizabeth Sapey",

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doi = "10.52964/amja.0848",

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T1 - The changing characteristics of COVID-19 presentations

T2 - a regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave

AU - Atkin, Catherine

AU - Kamwa, Vicky

AU - Reddy-Kolanu, V

AU - Parekh, D

AU - Evison, Felicity

AU - Nightingale, Peter

AU - Gallier, Suzy

AU - Ball, Simon

AU - Sapey, Elizabeth

PY - 2021/7/6

Y1 - 2021/7/6

N2 - Background: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus.Methods: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days.Results: Wave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions.Conclusion: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.

AB - Background: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus.Methods: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days.Results: Wave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions.Conclusion: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.

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DO - 10.52964/amja.0848

M3 - Article

SN - 1747-4884

VL - 20

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JO - Acute Medicine

JF - Acute Medicine

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The changing characteristics of COVID-19 presentations: a regional comparison of SARS-CoV-2 hospitalised patients during the first and second wave

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