Abstract
The association of obesity with both hand and knee osteoarthritis (OA) is suggestive of a link between dysfunctional metabolism and joint integrity. Given the role of adipokines in mediating bone and cartilage homeostasis, we undertook this study to examine the relationship between adipokines and bone and cartilage biomarkers in a population of subjects with OA, and to determine whether adipokine levels predicted 2-year cartilage integrity.
Original language | English |
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Pages (from-to) | 700-7 |
Number of pages | 8 |
Journal | Arthritis & Rheumatism |
Volume | 63 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2011 |
Bibliographical note
Copyright © 2011 by the American College of Rheumatology.Keywords
- Obesity
- Bone and Bones
- Osteocalcin
- Humans
- Cartilage, Articular
- Aged
- Predictive Value of Tests
- Resistin
- Procollagen
- Longitudinal Studies
- Osteoarthritis, Knee
- Leptin
- Peptide Fragments
- Risk Factors
- Adiponectin
- Middle Aged
- Time Factors
- Adipokines
- Biological Markers
- Female
- Male