TY - JOUR
T1 - Telomeres and telomerases: intimations of immortality
AU - Crocker, John
PY - 2001/8/1
Y1 - 2001/8/1
N2 - There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immortalization'. Telomeres, structures that cap the chromosomes, are related to cell longevity and are regulated by a ribonucleoprotein called telomerase. This review describes the possible roles of telomeres and telomerase in the malignant process.
AB - There is a constant balance in cancer cells between division and death. The malignant phenotype is associated with a continuing cell cycle or 'immortalization'. Telomeres, structures that cap the chromosomes, are related to cell longevity and are regulated by a ribonucleoprotein called telomerase. This review describes the possible roles of telomeres and telomerase in the malignant process.
UR - http://www.scopus.com/inward/record.url?scp=0034886138&partnerID=8YFLogxK
U2 - 10.1097/00042737-200108000-00002
DO - 10.1097/00042737-200108000-00002
M3 - Article
C2 - 11507350
VL - 13
SP - 889
EP - 890
JO - European Journal of Gastroenterology & Hepatology
JF - European Journal of Gastroenterology & Hepatology
IS - 8
ER -