Targeting effectors:: the molecular recognition of Type III secreted proteins

Roland Arnold; Andre Jehl; Thomas Rattei

doi:10.1016/j.micinf.2010.02.003

Targeting effectors: the molecular recognition of Type III secreted proteins

Roland Arnold, Andre Jehl, Thomas Rattei

Cancer and Genomic Sciences

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review.

Original language	English
Pages (from-to)	346-58
Number of pages	13
Journal	Microbes and Infection
Volume	12
Issue number	5
Early online date	21 Feb 2010
DOIs	https://doi.org/10.1016/j.micinf.2010.02.003
Publication status	Published - May 2010

Keywords

Bacterial Proteins
Gram-Negative Bacteria
Membrane Transport Proteins
Models, Biological
Protein Transport
Virulence Factors
Journal Article
Review

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10.1016/j.micinf.2010.02.003Licence: None: All rights reserved

https://www.sciencedirect.com/science/article/pii/S1286457910000511Licence: None: All rights reserved

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title = "Targeting effectors:: the molecular recognition of Type III secreted proteins",

abstract = "The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review.",

keywords = "Bacterial Proteins, Gram-Negative Bacteria, Membrane Transport Proteins, Models, Biological, Protein Transport, Virulence Factors, Journal Article, Review",

author = "Roland Arnold and Andre Jehl and Thomas Rattei",

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doi = "10.1016/j.micinf.2010.02.003",

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T2 - the molecular recognition of Type III secreted proteins

AU - Arnold, Roland

AU - Jehl, Andre

AU - Rattei, Thomas

PY - 2010/5

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N2 - The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review.

AB - The Type III secretion system (TTSS) facilitates the export of effector proteins from pathogenic and symbiotic Gram-negative bacteria into the cytosol of eukaryotic host cells. The current functional and evolutionary knowledge on the molecular recognition of TTSS substrates and computational models of the secretion signal are discussed in this review.

KW - Bacterial Proteins

KW - Gram-Negative Bacteria

KW - Membrane Transport Proteins

KW - Models, Biological

KW - Protein Transport

KW - Virulence Factors

KW - Journal Article

KW - Review

U2 - 10.1016/j.micinf.2010.02.003

DO - 10.1016/j.micinf.2010.02.003

M3 - Review article

C2 - 20178857

SN - 1286-4579

VL - 12

SP - 346

EP - 358

JO - Microbes and Infection

JF - Microbes and Infection

IS - 5

ER -

Targeting effectors: the molecular recognition of Type III secreted proteins

Abstract

Keywords

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