Target highlights in CASP13: experimental target structures through the eyes of their authors

Rosalba Lepore; Andriy Kryshtafovych; Markus Alahuhta; Harshul A. Veraszto; Yannick J. Bomble; Joshua C. Bufton; Alex N. Bullock; Cody Caba; Hongnan Cao; Owen R. Davies; Ambroise Desfosses; Matthew Dunne; Krzysztof Fidelis; Celia W. Goulding; Manickam Gurusaran; Irina Gutsche; Christopher J. Harding; Marcus D. Hartmann; Christopher S. Hayes; Andrzej Joachimiak; Petr G. Leiman; Peter Loppnau; Andrew L. Lovering; Vladimir V. Lunin; Karolina Michalska; Ignacio Mir‐sanchis; Alok Mitra; John Moult; George N. Phillips Jr; Daniel M. Pinkas; Phoebe A. Rice; Yufeng Tong; Maya Topf; Jonathan D. Walton; Torsten Schwede

doi:10.1002/prot.25805

Target highlights in CASP13: experimental target structures through the eyes of their authors

Rosalba Lepore, Andriy Kryshtafovych, Markus Alahuhta, Harshul A. Veraszto, Yannick J. Bomble, Joshua C. Bufton, Alex N. Bullock, Cody Caba, Hongnan Cao, Owen R. Davies, Ambroise Desfosses, Matthew Dunne, Krzysztof Fidelis, Celia W. Goulding, Manickam Gurusaran, Irina Gutsche, Christopher J. Harding, Marcus D. Hartmann, Christopher S. Hayes, Andrzej JoachimiakPetr G. Leiman, Peter Loppnau, Andrew L. Lovering, Vladimir V. Lunin, Karolina Michalska, Ignacio Mir‐sanchis, Alok Mitra, John Moult, George N. Phillips Jr, Daniel M. Pinkas, Phoebe A. Rice, Yufeng Tong, Maya Topf, Jonathan D. Walton, Torsten Schwede

Biosciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

213 Downloads (Pure)

Abstract

The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

Original language	English
Pages (from-to)	1037-1057
Number of pages	21
Journal	Proteins: structure, function, and bioinformatics
Volume	87
Issue number	12
Early online date	9 Sept 2019
DOIs	https://doi.org/10.1002/prot.25805
Publication status	Published - Dec 2019

Bibliographical note

Publisher Copyright:
© 2019 The Authors. Proteins: Structure, Function, and Bioinformatics published by Wiley Periodicals, Inc.

Keywords

CASP
protein structure prediction
cryo-EM
X-ray crystallography
CASP, protein structure prediction

ASJC Scopus subject areas

Molecular Biology
Structural Biology
Biochemistry

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Lepore_et_al_Target_highlights_in_CASP13_Proteins:_structure,_function,_and_bioinformatics_2019
Checked for eligibility: 15/10/2019
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Lepore, R., Kryshtafovych, A., Alahuhta, M., Veraszto, H. A., Bomble, Y. J., Bufton, J. C., Bullock, A. N., Caba, C., Cao, H., Davies, O. R., Desfosses, A., Dunne, M., Fidelis, K., Goulding, C. W., Gurusaran, M., Gutsche, I., Harding, C. J., Hartmann, M. D., Hayes, C. S., ... Schwede, T. (2019). Target highlights in CASP13: experimental target structures through the eyes of their authors. Proteins: structure, function, and bioinformatics, 87(12), 1037-1057. https://doi.org/10.1002/prot.25805

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title = "Target highlights in CASP13: experimental target structures through the eyes of their authors",

abstract = "The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.",

keywords = "CASP, protein structure prediction, cryo-EM, X-ray crystallography, CASP, protein structure prediction",

author = "Rosalba Lepore and Andriy Kryshtafovych and Markus Alahuhta and Veraszto, {Harshul A.} and Bomble, {Yannick J.} and Bufton, {Joshua C.} and Bullock, {Alex N.} and Cody Caba and Hongnan Cao and Davies, {Owen R.} and Ambroise Desfosses and Matthew Dunne and Krzysztof Fidelis and Goulding, {Celia W.} and Manickam Gurusaran and Irina Gutsche and Harding, {Christopher J.} and Hartmann, {Marcus D.} and Hayes, {Christopher S.} and Andrzej Joachimiak and Leiman, {Petr G.} and Peter Loppnau and Lovering, {Andrew L.} and Lunin, {Vladimir V.} and Karolina Michalska and Ignacio Mir‐sanchis and Alok Mitra and John Moult and {Phillips Jr}, {George N.} and Pinkas, {Daniel M.} and Rice, {Phoebe A.} and Yufeng Tong and Maya Topf and Walton, {Jonathan D.} and Torsten Schwede",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors. Proteins: Structure, Function, and Bioinformatics published by Wiley Periodicals, Inc.",

year = "2019",

month = dec,

doi = "10.1002/prot.25805",

language = "English",

volume = "87",

pages = "1037--1057",

journal = "Proteins: structure, function, and bioinformatics",

issn = "0887-3585",

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Lepore, R, Kryshtafovych, A, Alahuhta, M, Veraszto, HA, Bomble, YJ, Bufton, JC, Bullock, AN, Caba, C, Cao, H, Davies, OR, Desfosses, A, Dunne, M, Fidelis, K, Goulding, CW, Gurusaran, M, Gutsche, I, Harding, CJ, Hartmann, MD, Hayes, CS, Joachimiak, A, Leiman, PG, Loppnau, P, Lovering, AL, Lunin, VV, Michalska, K, Mir‐sanchis, I, Mitra, A, Moult, J, Phillips Jr, GN, Pinkas, DM, Rice, PA, Tong, Y, Topf, M, Walton, JD & Schwede, T 2019, 'Target highlights in CASP13: experimental target structures through the eyes of their authors', Proteins: structure, function, and bioinformatics, vol. 87, no. 12, pp. 1037-1057. https://doi.org/10.1002/prot.25805

TY - JOUR

T1 - Target highlights in CASP13

T2 - experimental target structures through the eyes of their authors

AU - Lepore, Rosalba

AU - Kryshtafovych, Andriy

AU - Alahuhta, Markus

AU - Veraszto, Harshul A.

AU - Bomble, Yannick J.

AU - Bufton, Joshua C.

AU - Bullock, Alex N.

AU - Caba, Cody

AU - Cao, Hongnan

AU - Davies, Owen R.

AU - Desfosses, Ambroise

AU - Dunne, Matthew

AU - Fidelis, Krzysztof

AU - Goulding, Celia W.

AU - Gurusaran, Manickam

AU - Gutsche, Irina

AU - Harding, Christopher J.

AU - Hartmann, Marcus D.

AU - Hayes, Christopher S.

AU - Joachimiak, Andrzej

AU - Leiman, Petr G.

AU - Loppnau, Peter

AU - Lovering, Andrew L.

AU - Lunin, Vladimir V.

AU - Michalska, Karolina

AU - Mir‐sanchis, Ignacio

AU - Mitra, Alok

AU - Moult, John

AU - Phillips Jr, George N.

AU - Pinkas, Daniel M.

AU - Rice, Phoebe A.

AU - Tong, Yufeng

AU - Topf, Maya

AU - Walton, Jonathan D.

AU - Schwede, Torsten

PY - 2019/12

Y1 - 2019/12

N2 - The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

AB - The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.

KW - CASP

KW - protein structure prediction

KW - cryo-EM

KW - X-ray crystallography

KW - CASP, protein structure prediction

UR - http://www.scopus.com/inward/record.url?scp=85071917045&partnerID=8YFLogxK

U2 - 10.1002/prot.25805

DO - 10.1002/prot.25805

M3 - Article

C2 - 31442339

SN - 0887-3585

VL - 87

SP - 1037

EP - 1057

JO - Proteins: structure, function, and bioinformatics

JF - Proteins: structure, function, and bioinformatics

IS - 12

ER -

Target highlights in CASP13: experimental target structures through the eyes of their authors

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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