Systematic integration of experimental data and models in systems biology

Peter Li, Joseph O Dada, Daniel Jameson, Irena Spasic, Neil Swainston, Kathleen Carroll, Warwick Dunn, Farid Khan, Naglis Malys, Hanan L Messiha, Evangelos Simeonidis, Dieter Weichart, Catherine Winder, Jill Wishart, David S Broomhead, Carole A Goble, Simon J Gaskell, Douglas B Kell, Hans V Westerhoff, Pedro MendesNorman W Paton

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)
123 Downloads (Pure)

Abstract

The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction of a model in order to define its components and their biochemical reactions, and corresponding parameters. Automating the assembly and use of systems biology models is dependent upon data integration processes involving the interoperation of data and analytical resources.
Original languageEnglish
Article number582
JournalBMC Bioinformatics
Volume11
DOIs
Publication statusPublished - 29 Nov 2010

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