Synthesis of the Asperparaline Core by a Radical Cascade

Peter Crick; Nigel Simpkins; A Highton

doi:10.1021/ol202769f

Synthesis of the Asperparaline Core by a Radical Cascade

Peter Crick
, Nigel Simpkins
, A Highton

Chemistry

Research output: Contribution to journal › Article

29 Citations (Scopus)

Abstract

A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.

Original language	English
Pages (from-to)	111114161459004-
Journal	Organic Letters
DOIs	https://doi.org/10.1021/ol202769f
Publication status	Published - 14 Nov 2011

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title = "Synthesis of the Asperparaline Core by a Radical Cascade",

abstract = "A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.",

author = "Peter Crick and Nigel Simpkins and A Highton",

year = "2011",

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doi = "10.1021/ol202769f",

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AU - Crick, Peter

AU - Simpkins, Nigel

AU - Highton, A

PY - 2011/11/14

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N2 - A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.

AB - A concise access to the pentacyclic core structure of the asperparalines is described. The key step is a radical cascade sequence comprised of a 1,6-hydrogen atom transfer followed by 6-exo-trig and 5-exo-trig cyclizations.

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M3 - Article

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JO - Organic Letters

JF - Organic Letters

ER -

Synthesis of the Asperparaline Core by a Radical Cascade

Abstract

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