Abstract
Mannosyltransferases play a crucial role in mycobacterial cell-wall biosynthesis and are potential new drug targets for the treatment of tuberculosis. Herein, we describe the synthesis of alpha-(1--> 2)- and alpha-(1 --> 6)-linked mannopyranosyl disaccharides possessing a 5-azidonaphthlene-1-sulfonamidoethyl group as photoaffinity probes for active-site labeling studies of mannosyl-transferases in Mycobacterium tuberculosis. (C) 2003 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 683-691 |
| Number of pages | 9 |
| Journal | Carbohydrate Research |
| Volume | 339 |
| DOIs | |
| Publication status | Published - 1 Jan 2004 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- disaccharide
- photoaffinity probe
- mannosyltransferases
- mycobacterium tuberculosis
- marmose
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