Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?

Helen McGettrick

doi:10.1186/s13075-019-1871-5

Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?

Helen McGettrick

Inflammation and Ageing

Research output: Contribution to journal › Editorial › peer-review

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Abstract

Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations - clinical practice and translational research.

Original language	English
Article number	90
Journal	Arthritis Research & Therapy
Volume	21
DOIs	https://doi.org/10.1186/s13075-019-1871-5
Publication status	Published - 8 Apr 2019

Bibliographical note

© The Author(s). 2019

Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Keywords

synovial biopsy
rheumatoid arthritis
synovial tissue analysis
standardisation
fibroblast
STB
RA

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title = "Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?",

abstract = "Rheumatoid arthritis is an immune-mediated inflammatory disease of the synovium. Yet we still lack robust tissue-specific (synovial) biomarkers that are able to guide clinical decisions and stratify patients according to their disease subgroup and predicted response to treatment. The EULAR Synovitis Study Group and the OMERACT synovial tissue biopsy (STB) Special Interests Group have undertaken a consensus exercise to identify factors that are important for the standardisation of STB handling and analytical procedures in two situations - clinical practice and translational research.",

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Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?

Abstract

Bibliographical note

Keywords

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