Synchrotron X-ray diffraction to understand crystallographic texture of enamel affected by Hunter syndrome

Malik Arshman Khan, Owen Addison, Alison James, Christian J. Hendriksz, Maisoon Al-jawad

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
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Abstract

Objective

To determine whether Hunter syndrome (MPS II) affects the crystallographic texture (preferred orientation) of enamel.

Design

Synchrotron X-ray diffraction, being a state of the art technique, has been used to determine the enamel crystallite orientation in enamel affected by Hunter syndrome (MPS II). The incisal, lingual and cervical regions of the MPS II affected tooth were observed and compared to healthy tooth.

Results

It was observed that there is a loss of organization of crystallites in deciduous incisal enamel affected by Hunter syndrome (MPS II) as compared to healthy deciduous enamel tissue. Generally it was observed that, in contrast to the healthy enamel, the enamel affected by MPS II possessed a lower crystallographic preferred orientation, with a more uniform spatial distribution; however, the enamel at the incisal tip was relatively unaffected.

Conclusion

Hunter syndrome affects the enamel texture in the lingual and cervical regions of the tooth.
Original languageEnglish
Pages (from-to)193-196
JournalArchives of Oral Biology
Volume80
Early online date20 Apr 2017
DOIs
Publication statusPublished - 1 Aug 2017

Keywords

  • Synchrotron X-ray diffraction
  • Enamel texture
  • Mucopolysaccharidosis II
  • Preferred orientation

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