Switching off oncogenic signals in chronic myeloid leukaemia

Junia Melo; David J Barnes

doi:10.1038/sj.thj.6200449

Switching off oncogenic signals in chronic myeloid leukaemia

Junia Melo^*, David J Barnes

^*Corresponding author for this work

Cancer and Genomic Sciences

Research output: Contribution to journal › Review article

Original language	English
Pages (from-to)	S183-7
Journal	The Haematology Journal
Volume	5 Suppl 3
DOIs	https://doi.org/10.1038/sj.thj.6200449
Publication status	Published - 2004

Keywords

Adenosine Triphosphate/metabolism
Antineoplastic Agents/pharmacology
Benzamides
Binding Sites/drug effects
Drug Design
Drug Resistance, Neoplasm
Enzyme Inhibitors/pharmacology
Fusion Proteins, bcr-abl/antagonists & inhibitors
Gene Expression Regulation, Leukemic/drug effects
Humans
Imatinib Mesylate
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy
MAP Kinase Signaling System/drug effects
Oncogenes
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation/drug effects
Piperazines/pharmacology
Protein Kinase Inhibitors
Protein Kinases
Protein Processing, Post-Translational/drug effects
Protein Serine-Threonine Kinases/antagonists & inhibitors
Protein Structure, Tertiary/drug effects
Proto-Oncogene Proteins/antagonists & inhibitors
Proto-Oncogene Proteins c-akt
Pyrimidines/pharmacology
RNA Interference
Signal Transduction/drug effects
TOR Serine-Threonine Kinases
ras Proteins/antagonists & inhibitors

Access to Document

10.1038/sj.thj.6200449

Cite this

@article{aca3f1ec3e7a423a93f73fe15d144c2c,

title = "Switching off oncogenic signals in chronic myeloid leukaemia",

keywords = "Adenosine Triphosphate/metabolism, Antineoplastic Agents/pharmacology, Benzamides, Binding Sites/drug effects, Drug Design, Drug Resistance, Neoplasm, Enzyme Inhibitors/pharmacology, Fusion Proteins, bcr-abl/antagonists & inhibitors, Gene Expression Regulation, Leukemic/drug effects, Humans, Imatinib Mesylate, Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy, MAP Kinase Signaling System/drug effects, Oncogenes, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation/drug effects, Piperazines/pharmacology, Protein Kinase Inhibitors, Protein Kinases, Protein Processing, Post-Translational/drug effects, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Structure, Tertiary/drug effects, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins c-akt, Pyrimidines/pharmacology, RNA Interference, Signal Transduction/drug effects, TOR Serine-Threonine Kinases, ras Proteins/antagonists & inhibitors",

author = "Junia Melo and Barnes, {David J}",

year = "2004",

doi = "10.1038/sj.thj.6200449",

language = "English",

volume = "5 Suppl 3",

pages = "S183--7",

journal = "The Haematology Journal",

issn = "1466-4860",

publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - Switching off oncogenic signals in chronic myeloid leukaemia

AU - Melo, Junia

AU - Barnes, David J

PY - 2004

Y1 - 2004

KW - Adenosine Triphosphate/metabolism

KW - Antineoplastic Agents/pharmacology

KW - Benzamides

KW - Binding Sites/drug effects

KW - Drug Design

KW - Drug Resistance, Neoplasm

KW - Enzyme Inhibitors/pharmacology

KW - Fusion Proteins, bcr-abl/antagonists & inhibitors

KW - Gene Expression Regulation, Leukemic/drug effects

KW - Humans

KW - Imatinib Mesylate

KW - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy

KW - MAP Kinase Signaling System/drug effects

KW - Oncogenes

KW - Phosphoinositide-3 Kinase Inhibitors

KW - Phosphorylation/drug effects

KW - Piperazines/pharmacology

KW - Protein Kinase Inhibitors

KW - Protein Kinases

KW - Protein Processing, Post-Translational/drug effects

KW - Protein Serine-Threonine Kinases/antagonists & inhibitors

KW - Protein Structure, Tertiary/drug effects

KW - Proto-Oncogene Proteins/antagonists & inhibitors

KW - Proto-Oncogene Proteins c-akt

KW - Pyrimidines/pharmacology

KW - RNA Interference

KW - Signal Transduction/drug effects

KW - TOR Serine-Threonine Kinases

KW - ras Proteins/antagonists & inhibitors

U2 - 10.1038/sj.thj.6200449

DO - 10.1038/sj.thj.6200449

M3 - Review article

C2 - 15190305

SN - 1466-4860

VL - 5 Suppl 3

SP - S183-7

JO - The Haematology Journal

JF - The Haematology Journal

ER -