Switch I closure simultaneously promotes strong binding to actin and ADP in smooth muscle myosin

Keyphrases

• Stronger Binding 100%
• Actin 100%
• Conformational Change 100%
• Smooth muscle Myosin 100%
• Nucleotide Binding 66%
• Binding Cleft 66%
• Nucleotide-binding Pocket 66%
• Actin Binding 66%
• Active Sites 33%
• Structural Change 33%
• Tight 33%
• Substrate Binding 33%
• Biochemical Studies 33%
• Tryptophan 33%
• Myosin 33%
• Smooth muscle 33%
• Substrate Binding Site 33%
• P-loop 33%
• ATP Hydrolysis 33%
• Motor Protein 33%
• ATPase Cycle 33%
• Actomyosin 33%

Biochemistry, Genetics and Molecular Biology

• Actin 100%
• Adenosine Diphosphate 100%
• Myosin 100%
• Conformational Change 60%
• Binding Site 20%
• Active Site 20%
• Enzymatic Hydrolysis 20%
• Adenosine Triphosphate 20%
• Conformation 20%
• ATPase 20%
• Motion 20%
• Tryptophan 20%
• Molecular Motor 20%
• Myosin ATPase 20%
• Motor Protein 20%