Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions

Tristan P Learoyd; Jane L Burrows; Eddie French; Peter C Seville

doi:10.1080/02652040903052044

Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions

Tristan P Learoyd, Jane L Burrows, Eddie French, Peter C Seville

Pharmacy

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The sustained delivery of multiple agents to the lung offers potential benefits to patients. This study explores the preparation of highly respirable dual-loaded spray-dried double emulsions. Spray-dried powders were produced from water-in-oil-in-water (w/o/w) double emulsions, containing salbutamol sulphate and/or beclometasone dipropionate in varying phases. The double emulsions contained the drug release modifier polylactide co-glycolide (PLGA 50 : 50) in the intermediate organic phase of the original micro-emulsion and low molecular weight chitosan (Mw

Original language	English
Pages (from-to)	162-70
Number of pages	9
Journal	Journal of Microencapsulation
Volume	27
Issue number	2
DOIs	https://doi.org/10.1080/02652040903052044
Publication status	Published - 2010

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abstract = "The sustained delivery of multiple agents to the lung offers potential benefits to patients. This study explores the preparation of highly respirable dual-loaded spray-dried double emulsions. Spray-dried powders were produced from water-in-oil-in-water (w/o/w) double emulsions, containing salbutamol sulphate and/or beclometasone dipropionate in varying phases. The double emulsions contained the drug release modifier polylactide co-glycolide (PLGA 50 : 50) in the intermediate organic phase of the original micro-emulsion and low molecular weight chitosan (Mw",

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AU - Seville, Peter C

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DO - 10.1080/02652040903052044

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Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions

Abstract

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