Structural characterization of a partially arabinosylated lipoarabinomannan variant isolated from a Corynebacterium glutamicum ubiA mutant

RV Tatituri, Luke Alderwick, Arun Kumar Mishra, J Nigou, M Gilleron, K Krumbach, P Hitchen, A Giordano, HR Morris, A Dell, L Eggeling, Gurdyal Besra

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)
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Abstract

Arabinan polysaccharide side-chains are present in both Mycobacterium tuberculosis and Corynebacterium glutamicum in the heteropolysaccharide arabinogalactan (AG), and in M. tuberculosis in the lipoglycan, lipoarabinomannan (LAM). Herein, we show by quantitative sugar and glycosyl linkage analysis that C. glutamicum possesses a much smaller LAM version, Cg-LAM, characterised by single t-Araf residues linked to the
Original languageEnglish
Pages (from-to)2621-2629
Number of pages9
JournalMicrobiology
Volume153
Issue number8
DOIs
Publication statusPublished - 1 Aug 2007

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