Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution

Marcel Reese; Víctor M Sánchez-Pedregal; Karel Kubicek; Jens Meiler; Marcel J J Blommers; Christian Griesinger; Teresa Carlomagno

doi:10.1002/anie.200604505

Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution

Marcel Reese, Víctor M Sánchez-Pedregal, Karel Kubicek, Jens Meiler, Marcel J J Blommers, Christian Griesinger, Teresa Carlomagno

Biosciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1864-8
Number of pages	5
Journal	Angewandte Chemie (International Edition)
Volume	46
Issue number	11
DOIs	https://doi.org/10.1002/anie.200604505
Publication status	Published - 2007

Keywords

Antineoplastic Agents/chemistry
Epothilones/chemistry
Magnesium/chemistry
Magnetic Resonance Spectroscopy
Microtubules/chemistry
Models, Molecular
Solutions
Structure-Activity Relationship
Tubulin/chemistry

Access to Document

10.1002/anie.200604505

Cite this

@article{4f96dd282f4546cfab188c2fd7f85981,

title = "Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution",

keywords = "Antineoplastic Agents/chemistry, Epothilones/chemistry, Magnesium/chemistry, Magnetic Resonance Spectroscopy, Microtubules/chemistry, Models, Molecular, Solutions, Structure-Activity Relationship, Tubulin/chemistry",

author = "Marcel Reese and S{\'a}nchez-Pedregal, \{V{\'i}ctor M\} and Karel Kubicek and Jens Meiler and Blommers, \{Marcel J J\} and Christian Griesinger and Teresa Carlomagno",

year = "2007",

doi = "10.1002/anie.200604505",

language = "English",

volume = "46",

pages = "1864--8",

journal = "Angewandte Chemie (International Edition) ",

issn = "1433-7851",

publisher = "Wiley-VCH Verlag",

number = "11",

}

TY - JOUR

T1 - Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution

AU - Reese, Marcel

AU - Sánchez-Pedregal, Víctor M

AU - Kubicek, Karel

AU - Meiler, Jens

AU - Blommers, Marcel J J

AU - Griesinger, Christian

AU - Carlomagno, Teresa

PY - 2007

Y1 - 2007

KW - Antineoplastic Agents/chemistry

KW - Epothilones/chemistry

KW - Magnesium/chemistry

KW - Magnetic Resonance Spectroscopy

KW - Microtubules/chemistry

KW - Models, Molecular

KW - Solutions

KW - Structure-Activity Relationship

KW - Tubulin/chemistry

U2 - 10.1002/anie.200604505

DO - 10.1002/anie.200604505

M3 - Article

C2 - 17274084

SN - 1433-7851

VL - 46

SP - 1864

EP - 1868

JO - Angewandte Chemie (International Edition)

JF - Angewandte Chemie (International Edition)

IS - 11

ER -