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Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution

  • Marcel Reese
  • , Víctor M Sánchez-Pedregal
  • , Karel Kubicek
  • , Jens Meiler
  • , Marcel J J Blommers
  • , Christian Griesinger
  • , Teresa Carlomagno

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1864-8
Number of pages5
JournalAngewandte Chemie (International Edition)
Volume46
Issue number11
DOIs
Publication statusPublished - 2007

Keywords

  • Antineoplastic Agents/chemistry
  • Epothilones/chemistry
  • Magnesium/chemistry
  • Magnetic Resonance Spectroscopy
  • Microtubules/chemistry
  • Models, Molecular
  • Solutions
  • Structure-Activity Relationship
  • Tubulin/chemistry

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