Solving the WAVE function

Robert Insall; Simone Blagg

doi:10.1038/ncb0404-279

Solving the WAVE function

Robert Insall
, Simone Blagg

Biosciences

Research output: Contribution to journal › Review article

26 Citations (Scopus)

Abstract

SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.

Original language	English
Pages (from-to)	279-281
Number of pages	3
Journal	Nature Cell Biology
Volume	6
DOIs	https://doi.org/10.1038/ncb0404-279
Publication status	Published - 1 Jan 2004

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10.1038/ncb0404-279

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abstract = "SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.",

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AB - SCAR/WAVE proteins are central regulators of cell motility that coordinate actin reorganization through activation of the Arp2/3 complex. Their activity is controlled by a large complex with four other members. A new study contradicts earlier work by suggesting that the entire complex is required for SCAR/WAVE activity at the leading edge.

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M3 - Review article

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JO - Nature Cell Biology

JF - Nature Cell Biology

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Solving the WAVE function

Abstract

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