Single twin demise: consequence for survivors

Sarah Hillman, Rachel Morris

Research output: Contribution to journalArticle

16 Citations (Scopus)


Multiple pregnancies, the majority of which are twins, are at substantially higher risk of fetal morbidity and mortality when compared with singleton pregnancies. Single fetal demise occurs in up to 6.2% of all twin pregnancies. It may cause considerable risk for the co-twin including increased risk of fetal loss, premature delivery, neurovascular injury and end-organ damage. In this review we seek to summarise the most contemporary literature on the aetiology of single twin demise, the pathophysiology of injury to the surviving twin and the evidence for current management strategies.
Original languageEnglish
JournalSeminars in Fetal & Neonatal Medicine
Publication statusPublished - 26 Jun 2010


  • Single twin demise
  • Twin pregnancy
  • Intrauterine death


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