Siglec-5 (CD170) can mediate inhibitory signalling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation

Keyphrases

• Phosphorylation 100%
• Inhibitory Signaling 100%
• Siglec-5 100%
• Immunoreceptor Tyrosine-based Activation Motif 100%
• Tyrosine 40%
• Tyrosine Phosphorylation 30%
• Cytoplasmic Tail 30%
• Phenylalanine 30%
• SHP-1 30%
• CD33 20%
• Serotonin Release 20%
• Tyrosine Motif 20%
• SHP2 20%
• Siglec 20%
• Pullout 10%
• Red Blood Cells 10%
• Adhesion 10%
• Sialic Acid 10%
• Myeloid Cells 10%
• Microscopy 10%
• Lectin 10%
• Inhibitory Activity 10%
• Leukemia Cells 10%
• Signal Functions 10%
• Protein Tyrosine Phosphatase 1B (PTP1B) 10%
• Inhibitory Receptors 10%
• Strong Inhibition 10%
• Phosphatase Assay 10%
• Recombinant Form 10%
• Hemopoietic System 10%
• Co-crosslinking 10%
• Basophils 10%
• Synthetic Forms 10%

Biochemistry, Genetics and Molecular Biology

• Siglec 100%
• Immunoreceptor Tyrosine-Based Inhibitory Motif 100%
• Tyrosine 50%
• Alanine 25%
• Tyrosine Phosphorylation 25%
• Phenylalanine 25%
• CD33 16%
• Serotonin Release 16%
• Intravenous Immunoglobulin 8%
• Wild Type 8%
• Sialic Acid 8%
• Phosphatase 8%
• Myeloid 8%
• Lectin 8%
• Cross-Link 8%
• Protein Tyrosine Phosphatase 8%

Immunology and Microbiology

• Sialic Acid Binding Immunoglobulin Like Lectin 100%
• Immunoreceptor Tyrosine-Based Inhibitory Motif 100%
• Protein Phosphorylation 23%
• CD33 15%
• Serotonin Release 15%
• Cross Linking 7%
• Myeloid 7%
• Wild Type 7%
• Leukemia Cell 7%
• Basophil 7%