Should androgen supplementation be used for poor ovarian response in IVF?

SK Sunkara, Aravinthan Coomarasamy, Wiebke Arlt, S Bhattacharya

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    Abstract

    Poor ovarian response is reported in 924 of IVF cycles. Several interventions have been proposed to improve the outcome, although evidence to support these has been scant. There has been interest in the use of adjuvant androgens in this context and a recent worldwide survey showed that nearly a quarter of IVF clinicians used dehydroepiandrosterone (DHEA) in poor responders. We examine the rationale for the use of adjuvant androgens and suggest that the current clinical uncertainty should be addressed by a randomized controlled trial of DHEA in poor responders.
    Original languageEnglish
    Pages (from-to)637-640
    Number of pages4
    JournalHuman Reproduction
    Volume27
    Issue number3
    DOIs
    Publication statusPublished - 1 Mar 2012

    Keywords

    • poor ovarian response
    • androgens
    • IVF treatment

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