Severity of primary MPGN, rather than MPGN type, determines renal survival and post-transplantation recurrence risk

Mark Little; P Dupont; E Campbell; A Dorman; JJ Walshe

doi:10.1038/sj.ki.5000084

Severity of primary MPGN, rather than MPGN type, determines renal survival and post-transplantation recurrence risk

Mark Little, P Dupont, E Campbell, A Dorman, JJ Walshe

Immunology and Immunotherapy

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92 Citations (Scopus)

Abstract

Previous studies suggested that membranoproliferative glomerulonephritis (MPGN) type II has a worse renal survival and an unacceptable risk of recurrence post transplantation. We hypothesised that other factors may determine this risk. We analysed all cases (n=70) of MPGN diagnosed by renal biopsy in Ireland from 1972 to 1995. We used Cox regression analysis to determine factors that were independently predictive of renal failure. MPGN II had more crescent formation and mesangial proliferation (P

Original language	English
Pages (from-to)	504-11
Number of pages	8
Journal	Kidney International
Volume	69
DOIs	https://doi.org/10.1038/sj.ki.5000084
Publication status	Published - 4 Jan 2006

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abstract = "Previous studies suggested that membranoproliferative glomerulonephritis (MPGN) type II has a worse renal survival and an unacceptable risk of recurrence post transplantation. We hypothesised that other factors may determine this risk. We analysed all cases (n=70) of MPGN diagnosed by renal biopsy in Ireland from 1972 to 1995. We used Cox regression analysis to determine factors that were independently predictive of renal failure. MPGN II had more crescent formation and mesangial proliferation (P",

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AU - Dupont, P

AU - Campbell, E

AU - Dorman, A

AU - Walshe, JJ

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N2 - Previous studies suggested that membranoproliferative glomerulonephritis (MPGN) type II has a worse renal survival and an unacceptable risk of recurrence post transplantation. We hypothesised that other factors may determine this risk. We analysed all cases (n=70) of MPGN diagnosed by renal biopsy in Ireland from 1972 to 1995. We used Cox regression analysis to determine factors that were independently predictive of renal failure. MPGN II had more crescent formation and mesangial proliferation (P

AB - Previous studies suggested that membranoproliferative glomerulonephritis (MPGN) type II has a worse renal survival and an unacceptable risk of recurrence post transplantation. We hypothesised that other factors may determine this risk. We analysed all cases (n=70) of MPGN diagnosed by renal biopsy in Ireland from 1972 to 1995. We used Cox regression analysis to determine factors that were independently predictive of renal failure. MPGN II had more crescent formation and mesangial proliferation (P

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SN - 1523-1755

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JO - Kidney International

JF - Kidney International

ER -

Severity of primary MPGN, rather than MPGN type, determines renal survival and post-transplantation recurrence risk

Abstract

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