Screening and treatment of vitamin D deficiency in UK patients with crohn’s disease: Self-reported practice among gastroenterologists

Jane Fletcher; Amelia Swift; Martin Hewison; Sheldon C. Cooper

doi:10.3390/nu12041064

Screening and treatment of vitamin D deficiency in UK patients with crohn’s disease: Self-reported practice among gastroenterologists

Jane Fletcher^*, Amelia Swift, Martin Hewison, Sheldon C. Cooper

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Currently, there is no UK national recommendation to measure vitamin D levels in patients with inflammatory bowel diseases (IBD). Patients with IBD are at risk of developing vitamin D deficiency with the highest prevalence frequently reported in those with Crohn’s disease (CD). Treating vitamin D deficiency as part of CD management continues to be of interest. Our aim was to identify influences on practice and self-reported practice among British Society of Gastroenterology (BSG)-IBD section members in the screening and the treatment of vitamin D deficiency in patients with CD. A web-based survey was distributed via email to members of the BSG-IBD section. Reported screening practice was generally annual in those with a history of previous surgery related to CD or small bowel CD. A total of 83% of respondents (n = 64) thought that vitamin D levels should be routinely monitored in patients with CD. Treatments for mild/moderate deficiency included increased sunlight exposure (mean frequency = 21, SD = 15) and dietary advice (mean frequency = 22, SD = 14); in moderate/severe deficiency, oral supplementation was recommended (mean frequency = 14, SD = 13). Respondents reported factors most likely to influence practice, including clearer evidence and guidance. Well conducted studies in CD patients with identified vitamin D deficiency are needed to inform national guidance and clinical practice.

Original language	English
Article number	1064
Journal	Nutrients
Volume	12
Issue number	4
DOIs	https://doi.org/10.3390/nu12041064
Publication status	Published - Apr 2020

Bibliographical note

Funding Information:
This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017?03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. With thanks to the communications team of the British Society of Gastroenterology for their assistance in distributing the survey. With thanks to Professor Debbie Carrick-Sen, University of Birmingham, for her assistance in the early design phase of the survey.

Funding Information:
Conflicts of Interest: J.F. is in receipt of funding from National Institute for Health Research (NIHR) and has received honoraria from Avanos and B.D., M.H. reports personal fees from Internis, S.C.C. reports educational sponsorship from Takeda, Fresenius-Kabi and honoraria from Novartis and Baxter. A.S. reports no conflicts of interest.

Funding Information:
Funding: This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017–03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.

Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Clinical practice
Crohn’s disease
Screening
Vitamin D deficiency

ASJC Scopus subject areas

Food Science
Nutrition and Dietetics

Access to Document

10.3390/nu12041064

Cite this

@article{723e61822a3b4b898182ef74d4b061fe,

title = "Screening and treatment of vitamin D deficiency in UK patients with crohn{\textquoteright}s disease: Self-reported practice among gastroenterologists",

abstract = "Currently, there is no UK national recommendation to measure vitamin D levels in patients with inflammatory bowel diseases (IBD). Patients with IBD are at risk of developing vitamin D deficiency with the highest prevalence frequently reported in those with Crohn{\textquoteright}s disease (CD). Treating vitamin D deficiency as part of CD management continues to be of interest. Our aim was to identify influences on practice and self-reported practice among British Society of Gastroenterology (BSG)-IBD section members in the screening and the treatment of vitamin D deficiency in patients with CD. A web-based survey was distributed via email to members of the BSG-IBD section. Reported screening practice was generally annual in those with a history of previous surgery related to CD or small bowel CD. A total of 83% of respondents (n = 64) thought that vitamin D levels should be routinely monitored in patients with CD. Treatments for mild/moderate deficiency included increased sunlight exposure (mean frequency = 21, SD = 15) and dietary advice (mean frequency = 22, SD = 14); in moderate/severe deficiency, oral supplementation was recommended (mean frequency = 14, SD = 13). Respondents reported factors most likely to influence practice, including clearer evidence and guidance. Well conducted studies in CD patients with identified vitamin D deficiency are needed to inform national guidance and clinical practice.",

keywords = "Clinical practice, Crohn{\textquoteright}s disease, Screening, Vitamin D deficiency",

author = "Jane Fletcher and Amelia Swift and Martin Hewison and Cooper, {Sheldon C.}",

note = "Funding Information: This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017?03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. With thanks to the communications team of the British Society of Gastroenterology for their assistance in distributing the survey. With thanks to Professor Debbie Carrick-Sen, University of Birmingham, for her assistance in the early design phase of the survey. Funding Information: Conflicts of Interest: J.F. is in receipt of funding from National Institute for Health Research (NIHR) and has received honoraria from Avanos and B.D., M.H. reports personal fees from Internis, S.C.C. reports educational sponsorship from Takeda, Fresenius-Kabi and honoraria from Novartis and Baxter. A.S. reports no conflicts of interest. Funding Information: Funding: This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017–03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2020",

month = apr,

doi = "10.3390/nu12041064",

language = "English",

volume = "12",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "4",

}

TY - JOUR

T1 - Screening and treatment of vitamin D deficiency in UK patients with crohn’s disease

T2 - Self-reported practice among gastroenterologists

AU - Fletcher, Jane

AU - Swift, Amelia

AU - Hewison, Martin

AU - Cooper, Sheldon C.

N1 - Funding Information: This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017?03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. With thanks to the communications team of the British Society of Gastroenterology for their assistance in distributing the survey. With thanks to Professor Debbie Carrick-Sen, University of Birmingham, for her assistance in the early design phase of the survey. Funding Information: Conflicts of Interest: J.F. is in receipt of funding from National Institute for Health Research (NIHR) and has received honoraria from Avanos and B.D., M.H. reports personal fees from Internis, S.C.C. reports educational sponsorship from Takeda, Fresenius-Kabi and honoraria from Novartis and Baxter. A.S. reports no conflicts of interest. Funding Information: Funding: This publication presents independent research funded by the National Institute for Health Research (NIHR) and Health Education England through a Clinical Doctoral Research Fellowship, ICA-CDRF-2017–03-083. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2020/4

Y1 - 2020/4

N2 - Currently, there is no UK national recommendation to measure vitamin D levels in patients with inflammatory bowel diseases (IBD). Patients with IBD are at risk of developing vitamin D deficiency with the highest prevalence frequently reported in those with Crohn’s disease (CD). Treating vitamin D deficiency as part of CD management continues to be of interest. Our aim was to identify influences on practice and self-reported practice among British Society of Gastroenterology (BSG)-IBD section members in the screening and the treatment of vitamin D deficiency in patients with CD. A web-based survey was distributed via email to members of the BSG-IBD section. Reported screening practice was generally annual in those with a history of previous surgery related to CD or small bowel CD. A total of 83% of respondents (n = 64) thought that vitamin D levels should be routinely monitored in patients with CD. Treatments for mild/moderate deficiency included increased sunlight exposure (mean frequency = 21, SD = 15) and dietary advice (mean frequency = 22, SD = 14); in moderate/severe deficiency, oral supplementation was recommended (mean frequency = 14, SD = 13). Respondents reported factors most likely to influence practice, including clearer evidence and guidance. Well conducted studies in CD patients with identified vitamin D deficiency are needed to inform national guidance and clinical practice.

AB - Currently, there is no UK national recommendation to measure vitamin D levels in patients with inflammatory bowel diseases (IBD). Patients with IBD are at risk of developing vitamin D deficiency with the highest prevalence frequently reported in those with Crohn’s disease (CD). Treating vitamin D deficiency as part of CD management continues to be of interest. Our aim was to identify influences on practice and self-reported practice among British Society of Gastroenterology (BSG)-IBD section members in the screening and the treatment of vitamin D deficiency in patients with CD. A web-based survey was distributed via email to members of the BSG-IBD section. Reported screening practice was generally annual in those with a history of previous surgery related to CD or small bowel CD. A total of 83% of respondents (n = 64) thought that vitamin D levels should be routinely monitored in patients with CD. Treatments for mild/moderate deficiency included increased sunlight exposure (mean frequency = 21, SD = 15) and dietary advice (mean frequency = 22, SD = 14); in moderate/severe deficiency, oral supplementation was recommended (mean frequency = 14, SD = 13). Respondents reported factors most likely to influence practice, including clearer evidence and guidance. Well conducted studies in CD patients with identified vitamin D deficiency are needed to inform national guidance and clinical practice.

KW - Clinical practice

KW - Crohn’s disease

KW - Screening

KW - Vitamin D deficiency

UR - http://www.scopus.com/inward/record.url?scp=85083402657&partnerID=8YFLogxK

U2 - 10.3390/nu12041064

DO - 10.3390/nu12041064

M3 - Article

C2 - 32290515

AN - SCOPUS:85083402657

SN - 2072-6643

VL - 12

JO - Nutrients

JF - Nutrients

IS - 4

M1 - 1064

ER -

Screening and treatment of vitamin D deficiency in UK patients with crohn’s disease: Self-reported practice among gastroenterologists

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this