SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?

Jibran Sualeh Muhammad; Ruqaiyyah Siddiqui; Naveed Ahmed Khan

doi:10.1016/j.compbiolchem.2021.107602

SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?

Jibran Sualeh Muhammad^*, Ruqaiyyah Siddiqui, Naveed Ahmed Khan^*

^*Corresponding author for this work

Biomedical Sciences

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.

Original language	English
Article number	107602
Number of pages	3
Journal	Computational Biology and Chemistry
Volume	96
Early online date	20 Nov 2021
DOIs	https://doi.org/10.1016/j.compbiolchem.2021.107602
Publication status	Published - Feb 2022

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd

Keywords

COVID-19
Disease severity
Genetic changes
SARS-CoV-2
UVB radiation

ASJC Scopus subject areas

Structural Biology
Biochemistry
Organic Chemistry
Computational Mathematics

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Cite this

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title = "SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?",

abstract = "Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.",

keywords = "COVID-19, Disease severity, Genetic changes, SARS-CoV-2, UVB radiation",

author = "Muhammad, {Jibran Sualeh} and Ruqaiyyah Siddiqui and Khan, {Naveed Ahmed}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",

year = "2022",

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doi = "10.1016/j.compbiolchem.2021.107602",

language = "English",

volume = "96",

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AU - Muhammad, Jibran Sualeh

AU - Siddiqui, Ruqaiyyah

AU - Khan, Naveed Ahmed

PY - 2022/2

Y1 - 2022/2

N2 - Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.

AB - Herein it is proposed that sufficient exposure to sunlight (UVB) modulates host gene expression, offering protection against severe consequences of COVID-19. This could be in addition to sunlight (UVB)-mediated protection by directly inactivating the virus and limiting the viral load. It is suggested that inhibition of CCR2, DPP9, HSPA1L, IFNAR2, OAS1, and TYK2 may, in part, explain UVB-mediated protection against severe consequences of COVID-19.

KW - COVID-19

KW - Disease severity

KW - Genetic changes

KW - SARS-CoV-2

KW - UVB radiation

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U2 - 10.1016/j.compbiolchem.2021.107602

DO - 10.1016/j.compbiolchem.2021.107602

M3 - Comment/debate

C2 - 34823125

AN - SCOPUS:85119507395

SN - 1476-9271

VL - 96

JO - Computational Biology and Chemistry

JF - Computational Biology and Chemistry

M1 - 107602

ER -

SARS-CoV-2: Can sunlight exposure reduce the risk of developing severe consequences of COVID-19?

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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