Reduced kidney function at presentation in unselected acute emergency medical admissions: incidence, outcome and associated factors

E Yang, A Chalisey, M E Reschen, B Shine, Dan Lasserson, C A O'Callaghan

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

We sought to assess the impact of renal impairment on acute medical admissions and to identify potential contributory factors to admissions involving renal impairment at presentation. In a prospective cohort study, 29.5% of all acute medical emergency admissions had an eGFR <60ml/min/1.73m2 at presentation. Of these, 19.9% had definite chronic kidney disease and 8.4% had definite acute kidney injury. Detailed analysis of a random subset of patients with an eGFR <60ml/min/1.73m2 at presentation demonstrated that the major reasons for admission included falls, dehydration and fluid overload. 46% were on diuretics and 53% were on an ACEI or ARB or both. Gastrointestinal disturbance and recent medication changes were common and diuretic use persisted even with diarrhoea or vomiting.

Original languageEnglish
Pages (from-to)158-164
Number of pages7
JournalAcute Medicine
Volume18
Issue number3
Publication statusPublished - 19 Sep 2019

Keywords

  • Acute kidney injury
  • Acute medicine
  • Chronic kidney disease
  • Hospital admission
  • Kidney function

ASJC Scopus subject areas

  • Internal Medicine
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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