Reconfiguration from emergency to urgent elective neurosurgery for glioblastoma patients improves length of stay, surgical adjunct use, and extent of resective surgery

Rosa Sun, Shivam Sharma, Helen Benghiat, Sara Meade, Paul Sanghera, Gregory Bramwell, Santhosh Nagaraju, Ute Pohl, Camilla Dawson, Vladimir Petrik, Ismail Ughratdar, Anwen White, Athanasios Zisakis, Satheesh Ramalingam, Vijay Sawlani, Colin Watts, Victoria Wykes

Research output: Contribution to journalArticlepeer-review

118 Downloads (Pure)

Abstract

Background

Glioblastoma (GB) is the most common intrinsic brain cancer and is notorious for its aggressive nature. Despite widespread research and optimization of clinical management, the improvement in overall survival has been limited. The aim of this study was to characterize the impact of service reconfiguration on GB outcomes in a single centre.
Methods

Patients with a histopathological confirmation of a diagnosis of GB between 01/01/2014 and 31/12/2019 were retrospectively identified. Demographic and tumour characteristics, survival, treatment (surgical and oncological), admission status, use of surgical adjunct (5-aminolevulinic acid, intra-operative neuro-monitoring), the length of stay, extent of resection, and surgical complications were recorded from the hospital databases.
Results

From August 2018 the neurosurgical oncology service was reconfigured to manage high-grade tumours on an urgent outpatient basis by surgeons specializing in oncology. We demonstrate that these changes resulted in an increase in elective admissions, greater use of intra-operative adjuncts resulting in the improved extent of tumour resection, and a reduction in median length of stay and associated cost-savings.
Conclusions

Optimizing neuro-oncology patient management through service reconfiguration resulted in increased use of intra-operative adjuncts, improved surgical outcomes, and reduced hospital costs. These changes also have the potential to improve survival and disease-free progression for patients with GB.
Original languageEnglish
Article numbernpac034
Pages (from-to)1-9
Number of pages9
JournalNeuro-Oncology Practice
DOIs
Publication statusPublished - 2 May 2022

Keywords

  • glioblastoma
  • health services
  • neuro-oncology
  • Neurosurgery
  • oncology
  • practice

Fingerprint

Dive into the research topics of 'Reconfiguration from emergency to urgent elective neurosurgery for glioblastoma patients improves length of stay, surgical adjunct use, and extent of resective surgery'. Together they form a unique fingerprint.

Cite this