Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report

Pierre-Alain Clavien, Mickael Lesurtel, Patrick M M Bossuyt, Gregory J Gores, Bernard Langer, Arnaud Perrier, OLT for HCC Consensus Group

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618 Citations (Scopus)


Although liver transplantation is a widely accepted treatment for hepatocellular carcinoma (HCC), much controversy remains and there is no generally accepted set of guidelines. An international consensus conference was held on Dec 2-4, 2010, in Zurich, Switzerland, with the aim of reviewing current practice regarding liver transplantation in patients with HCC and to develop internationally accepted statements and guidelines. The format of the conference was based on the Danish model. 19 working groups of experts prepared evidence-based reviews according to the Oxford classification, and drafted recommendations answering 19 specific questions. An independent jury of nine members was appointed to review these submissions and make final recommendations, after debates with the experts and audience at the conference. This report presents the final 37 statements and recommendations, covering assessment of candidates for liver transplantation, criteria for listing in cirrhotic and non-cirrhotic patients, role of tumour downstaging, management of patients on the waiting list, role of living donation, and post-transplant management.

Original languageEnglish
Pages (from-to)e11-22
JournalThe Lancet Oncology
Issue number1
Publication statusPublished - Jan 2012
Externally publishedYes


  • Carcinoma, Hepatocellular
  • Evidence-Based Medicine
  • Humans
  • Liver Neoplasms
  • Liver Transplantation
  • Neoadjuvant Therapy
  • Patient Selection
  • Risk Assessment
  • Risk Factors
  • Tissue Donors
  • Treatment Outcome
  • Waiting Lists


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