Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision

Lorenzo Cortese; Giuseppe Lo Presti; Marco Pagliazzi; Davide Contini; Alberto Dalla Mora; Hamid Dehghani; Fabio Ferri; Jonas B Fischer; Martina Giovannella; Fabrizio Martelli; Udo M Weigel; Stanislaw Wojtkiewicz; Marta Zanoletti; Turgut Durduran

doi:10.1364/BOE.423071

Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision

Lorenzo Cortese, Giuseppe Lo Presti, Marco Pagliazzi, Davide Contini, Alberto Dalla Mora, Hamid Dehghani, Fabio Ferri, Jonas B Fischer, Martina Giovannella, Fabrizio Martelli, Udo M Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Turgut Durduran

Computer Science

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Abstract

Over the recent years, a typical implementation of diffuse correlation spectroscopy (DCS) instrumentation has been adapted widely. However, there are no detailed and accepted recipes for designing such instrumentation to meet pre-defined signal-to-noise ratio (SNR) and precision targets. These require specific attention due to the subtleties of the DCS signals. Here, DCS experiments have been performed using liquid tissue simulating phantoms to study the effect of the detected photon count-rate, the number of parallel detection channels and the measurement duration on the precision and SNR to suggest scaling relations to be utilized for device design.

Original language	English
Pages (from-to)	3265-3281
Number of pages	17
Journal	Biomedical Optics Express
Volume	12
Issue number	6
Early online date	11 May 2021
DOIs	https://doi.org/10.1364/BOE.423071
Publication status	Published - 1 Jun 2021

Bibliographical note

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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10.1364/BOE.423071Licence: Other (please provide link to licence statement

CorteseL2021Recipes
https://doi.org/10.1364/BOE.423071 © 2021 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
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Cortese, L., Lo Presti, G., Pagliazzi, M., Contini, D., Dalla Mora, A., Dehghani, H., Ferri, F., Fischer, J. B., Giovannella, M., Martelli, F., Weigel, U. M., Wojtkiewicz, S., Zanoletti, M., & Durduran, T. (2021). Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision. Biomedical Optics Express, 12(6), 3265-3281. https://doi.org/10.1364/BOE.423071

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abstract = "Over the recent years, a typical implementation of diffuse correlation spectroscopy (DCS) instrumentation has been adapted widely. However, there are no detailed and accepted recipes for designing such instrumentation to meet pre-defined signal-to-noise ratio (SNR) and precision targets. These require specific attention due to the subtleties of the DCS signals. Here, DCS experiments have been performed using liquid tissue simulating phantoms to study the effect of the detected photon count-rate, the number of parallel detection channels and the measurement duration on the precision and SNR to suggest scaling relations to be utilized for device design.",

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Cortese, L, Lo Presti, G, Pagliazzi, M, Contini, D, Dalla Mora, A, Dehghani, H, Ferri, F, Fischer, JB, Giovannella, M, Martelli, F, Weigel, UM, Wojtkiewicz, S, Zanoletti, M & Durduran, T 2021, 'Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision', Biomedical Optics Express, vol. 12, no. 6, pp. 3265-3281. https://doi.org/10.1364/BOE.423071

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AU - Cortese, Lorenzo

AU - Lo Presti, Giuseppe

AU - Pagliazzi, Marco

AU - Contini, Davide

AU - Dalla Mora, Alberto

AU - Dehghani, Hamid

AU - Ferri, Fabio

AU - Fischer, Jonas B

AU - Giovannella, Martina

AU - Martelli, Fabrizio

AU - Weigel, Udo M

AU - Wojtkiewicz, Stanislaw

AU - Zanoletti, Marta

AU - Durduran, Turgut

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Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision

Abstract

Bibliographical note

ASJC Scopus subject areas

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