Recent trends in the use of electrical neuromodulation in Parkinson's disease

John-Stuart Brittain, Hayriye Cagnan

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)
114 Downloads (Pure)

Abstract

Purpose of review - This review aims to survey recent trends in electrical forms of neuromodulation, with a specific application to Parkinson's disease (PD). Emerging trends are identified, highlighting synergies in state-of-the-art neuromodulation strategies, with directions for future improvements in stimulation efficacy suggested.

Recent findings - Deep brain stimulation remains the most common and effective form of electrical stimulation for the treatment of PD. Evidence suggests that transcranial direct current stimulation (tDCS) most likely impacts the motor symptoms of the disease, with the most prominent results relating to rehabilitation. However, utility is limited due to its weak effects and high variability, with medication state a key confound for efficacy level. Recent innovations in transcranial alternating current stimulation (tACS) offer new areas for investigation.

Summary - Our understanding of the mechanistic foundations of electrical current stimulation is advancing and as it does so, trends emerge which steer future clinical trials towards greater efficacy.
Original languageEnglish
Pages (from-to)170-178
Number of pages9
JournalCurrent Behavioral Neuroscience Reports
Volume5
Issue number2
Early online date24 Apr 2018
DOIs
Publication statusPublished - Jun 2018

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