Quality of life in patients with atrial fibrillation: how to assess it and how to improve it

Etienne Aliot, Giovanni L Botto, Harry J Crijns, Paulus Kirchhof

Research output: Contribution to journalArticlepeer-review

53 Citations (Scopus)


Atrial fibrillation (AF) is the most frequent cardiac rhythm disorder and presents a considerable public health burden that is likely to increase in the next decades due to the ageing population. Current management strategies focus on the heart rate and rhythm control, thromboembolism prevention, and treatment of underlying diseases. The concept of quality of life (QoL) has gained significant importance in recent years as an outcome measure in AF studies evaluating therapeutic interventions and as a relevant component of a comprehensive treatment plan. Quality of life is impaired in the majority of patients with AF, and both rate and rhythm control strategies show significant improvement in QoL measures in highly symptomatic patients. This article reviews generic and specialized instruments for measuring QoL in the context of AF, discusses their applications and limitations to integration in clinical practice, and addresses the potential of early therapy for improving QoL outcomes. The development and validation of new QoL assessment tools will have a central role in the advancement of therapies and treatment guidelines for AF.

Original languageEnglish
Pages (from-to)787-96
Number of pages10
Issue number6
Publication statusPublished - Jun 2014


  • Atrial Fibrillation
  • Humans
  • Outcome Assessment (Health Care)
  • Quality Assurance, Health Care
  • Quality Improvement
  • Quality of Life
  • Questionnaires
  • Severity of Illness Index
  • Treatment Outcome


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