Psychotic episode secondary to gonadotrophins

José Daniel Machado Rodrigues; Maria Georgina Santos Lapa; Ian Fraser Brockington

doi:10.1016/j.genhosppsych.2014.05.016

Psychotic episode secondary to gonadotrophins

José Daniel Machado Rodrigues, Maria Georgina Santos Lapa, Ian Fraser Brockington

Birmingham Medical School

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

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Abstract

Objective
To report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.

Method
Case report.

Results
We report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.

Conclusion
There have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.

Original language	English
Pages (from-to)	549.e7-549.e8
Journal	General Hospital Psychiatry
Volume	36
Issue number	5
Early online date	2 Jun 2014
DOIs	https://doi.org/10.1016/j.genhosppsych.2014.05.016
Publication status	Published - 1 Sept 2014

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10.1016/j.genhosppsych.2014.05.016

Brockington_Psychotic_episode_General_Hospital_Psychiatry_2014
NOTICE: this is the author’s version of a work that was accepted for publication in General Hospital Psychiatry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in General Hospital Psychiatry, [VOL 36, ISSUE 5, September-October 2014] DOI: 10.1016/j.genhosppsych.2014.05.016 Eligibility for repository checked October 2014
Accepted author manuscript, 462 KBLicence: Other (please specify with Rights Statement)

http://linkinghub.elsevier.com/retrieve/pii/S0163834314001509

Cite this

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abstract = "ObjectiveTo report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.MethodCase report.ResultsWe report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.ConclusionThere have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.",

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AU - Rodrigues, José Daniel Machado

AU - Lapa, Maria Georgina Santos

AU - Brockington, Ian Fraser

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N2 - ObjectiveTo report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.MethodCase report.ResultsWe report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.ConclusionThere have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.

AB - ObjectiveTo report a case of a substance-induced psychotic disorder secondary to ovulation induction therapy with gonadotrophins.MethodCase report.ResultsWe report a case of a psychotic episode secondary to gonadotrophins therapy. The acute episode was treated with antipsychotic (Aripiprazole). After 2 years the patient remains free of psychotic symptoms.ConclusionThere have been several reports correlating low levels of estrogen with psychotic symptoms, leading to studies evaluating the possible effect of this hormone as an antipsychotic. In this case, we report psychotic symptoms with high levels of estradiol, which is contrary to that theory.

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DO - 10.1016/j.genhosppsych.2014.05.016

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VL - 36

SP - 549.e7-549.e8

JO - General Hospital Psychiatry

JF - General Hospital Psychiatry

IS - 5

ER -

Psychotic episode secondary to gonadotrophins

Abstract

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